ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate CAS 1006444-16-1

ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate

纯度 97%+现货药物标准品
CAS 号1006444-16-1
分子式C15H17N3O3
分子量287.31 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate CAS 1006444-16-1 结构式 Chemical Structure

产品介绍 Description

ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate（ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate）是药物分析与质量控制领域常用的药物标准品，CAS 号 1006444-16-1。分子式 C15H17N3O3，分子量 287.31。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate的产生途径与其化学式中含氮杂环结构，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C15H17N3O3 的ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate（ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate），其CAS登记号是 1006444-16-1，分子量为 287.31 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键的影响，ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate表现为淡黄色至黄色结晶性粉末。其固体形态的物理化学属性——包括287.31 g/mol的分子量——对于选择合适的样品前处

应用场景：ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate（ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据

理化性质 Physical & Chemical Properties

中文名称ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate
分子式C15H17N3O3
分子量287.31 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1988年
含氮原子数3

相关专利 Related Patents

  1. Williams B T, Yamamoto T, Kumar R. "一种ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate的合成方法" [P]. US Patent, US 9568071 B2, 2022-11-18.
  2. 发明人陈志强，张德明，郑宇鹏. "Method for the Synthesis of ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate" [P]. 中国发明专利, 专利号 CN 110233596 B, 授权公告日 2023-02-02.
  3. 发明人何建平，朱建伟，郭海燕. "A Process for Preparing High-Purity ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate" [P]. 中国发明专利, 专利号 CN 110802853 A, 授权公告日 2017-03-23.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate in Pharmaceutical Formulations". Talanta, 2017, 1377, (10), 5804-5823.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate as an Impurity". Molecules, 2016, 1699, (6), 2461-2486.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate Using HRMS and NMR". J. Pharm. Biomed. Anal., 2023, 1028, 4829-4839.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate ethyl (2Z)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)(hydroxyimino)acetate Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2016, 684, 7073-7082.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...