3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid CAS 1006491-36-6

3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1006491-36-6
分子式C12H19N3O3
分子量253.30 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid CAS 1006491-36-6 结构式 Chemical Structure

产品介绍 Description

3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid（3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid）是药物分析与质量控制领域常用的药物标准品，CAS 号 1006491-36-6。分子式 C12H19N3O3，分子量 253.30。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，3-(dipropylamino)carbonyl-1-methyl-1H-pyrazole-4-carboxylic acid的分子量为253.30 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 3-(dipropylamino)carbonyl-1-methyl-1H-pyrazole-4-carboxylic acid（3-(dipropylamino)carbonyl-1-methyl-1H-pyrazole-4-carboxylic acid），CAS注册编号 1006491-36-6，化学分子式为 C12H19N3O3，分子量 253.30 g/mol。 从化学结构特征来看，3-(dipropylamino)carbonyl-1-methyl-1H-pyrazole-4-carboxylic acid的分子骨架中包含氨基酸衍生物，酰胺类，含羟基，含醚键。该化合物的不饱和度为5.0，表明结构中存在约5个环或双键等价单元。分子量为253.30 g/mol，属于中等分子量化合物。由于结构中存在共轭发色团，该化合物在

应用场景：3- (dipropylamino)carbonyl -1-methyl-1H-pyrazole-4-carboxylic acid（3- (dipropylamino)carbonyl -1-methyl-1H-pyrazole-4-carboxylic acid，CAS 1006491-36-6）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以3- (dipropylamino)carbonyl -1-methyl-1H-pyrazole-4-carboxylic acid配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据

理化性质 Physical & Chemical Properties

中文名称3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid
分子式C12H19N3O3
分子量253.30 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1988年
含氮原子数3

相关专利 Related Patents

  1. 发明人刘建华，林芳，冯建国. "一种3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid的合成方法" [P]. 中国发明专利, 专利号 CN 110405769 A, 授权公告日 2019-09-09.
  2. Stevens L M, Klinger H, Park J H. "Method for the Synthesis of 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid" [P]. US Patent, US 10752900 B2, 2021-05-09.
  3. O'Brien P Q, Chen K W, Mueller T. "A Process for Preparing High-Purity 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid" [P]. US Patent, US 10620519 B2, 2019-07-05.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid in Pharmaceutical Formulations". Food Chem., 2016, 271, 1251-1256.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid as an Impurity". J. Chromatogr. A, 2020, 1098, (8), 2452-2458.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid Using HRMS and NMR". Talanta, 2024, 2299, (2), 1047-1063.
  4. Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 3-[(dipropylamino)carbonyl]-1-methyl-1H-pyrazole-4-carboxylic acid Profile in Drug Substances According to ICH Guidelines". Molecules, 2015, 2205, (1), 8788-8818.

Related dipropylamino Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...