CAS 101246-68-8

6PZZ52D76Q 101246-68-8 Eptastigmine Eptastigmine [INN] Physostigmine heptyl Carbamic acid, heptyl-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)- N-Demethyl-N-heptylphysostigmine BRN 4883778 Eptastigmina [INN-Spanish] Eptastigminum [INN-Latin] (-)-Heptylphysostigmine Eptastigmina Eptastigminum UNII-6PZZ52D76Q

纯度 97%+现货药物标准品
CAS 号101246-68-8
分子式C21H33N3O2
分子量359.51 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6PZZ52D76Q 101246-68-8 Eptastigmine Eptastigmine [INN] Physostigmine heptyl Carbamic acid, heptyl-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)- N-Demethyl-N-heptylphysostigmine BRN 4883778 Eptastigmina [INN-Spanish] Eptastigminum [INN-Latin] (-)-Heptylphysostigmine Eptastigmina Eptastigminum UNII-6PZZ52D76Q CAS 101246-68-8 结构式 Chemical Structure

产品介绍 Description

（6PZZ52D76Q 101246-68-8 Eptastigmine Eptastigmine [INN] Physostigmine heptyl Carbamic acid, heptyl-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)- N-Demethyl-N-heptylphysostigmine BRN 4883778 Eptastigmina [INN-Spanish] Eptastigminum [INN-Latin] (-)-Heptylphysostigmine Eptastigmina Eptastigminum UNII-6PZZ52D76Q，CAS 号 101246-68-8）是 CATO 佳途自主生产的药物标准品，分子式 C21H33N3O2，分子量 359.51。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在质量保证方面，的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 化学式为 C21H33N3O2 的（6PZZ52D76Q 101246-68-8 Eptastigmine Eptastigmine INN Physostigmine heptyl Carbamic acid, heptyl-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)- N-Demethyl-N-heptylphysostigmine BRN 4883778 Eptastigmina INN-Spanish Eptastigminum INN-Latin (-)-Heptylphysostigmine Eptastigmina Eptastigminum UNII-6

应用场景：（6PZZ52D76Q 101246-68-8 Eptastigmine Eptastigmine INN Physostigmine heptyl Carbamic acid, heptyl-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)- N-Demethyl-N-heptylphysostigmine BRN 4883778 Eptastigmina INN-Spanish Eptastigminum INN-Latin (-)-Heptylphysosti

理化性质 Physical & Chemical Properties

中文名称
分子式C21H33N3O2
分子量359.51 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1985年
含氮原子数3

相关专利 Related Patents

  1. 发明人何建平，朱建伟，陈志强. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 108327647 A, 授权公告日 2015-01-24.
  2. Schröder R, Mueller T, Kumar R. "Method for the Synthesis of 6PZZ52D76Q 101246-68-8 Eptastigmine Eptastigmine [INN] Physostigmine heptyl Carbamic acid, heptyl-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)- N-Demethyl-N-heptylphysostigmine BRN 4883778 Eptastigmina [INN-Spanish] Eptastigminum [INN-Latin] (-)-Heptylphysostigmine Eptastigmina Eptastigminum UNII-6PZZ52D76Q" [P]. US Patent, US 10427953 B2, 2016-06-25.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2013, 1094, 3240-3264.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Chromatographia, 2017, 1060, 5027-5030.

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