CAS 103412-40-4

103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-bradykinin

纯度 97%+现货药物标准品
CAS 号103412-40-4
分子式C62H95N19O14S2
分子量1394.67 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-bradykinin CAS 103412-40-4 结构式 Chemical Structure

产品介绍 Description

（103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-bradykinin，CAS 号 103412-40-4）是 CATO 佳途自主生产的药物标准品，分子式 C62H95N19O14S2，分子量 1394.67。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

化学式为 C62H95N19O14S2 的（103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-b

应用场景：（103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-

理化性质 Physical & Chemical Properties

中文名称
分子式C62H95N19O14S2
分子量1394.67 g/mol
外观形态淡黄色至黄色无定形粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）25.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1986年
含氮原子数19
含硫原子数2

相关专利 Related Patents

  1. Fischer A B, Roberts E F, Kumar R. "一种的合成方法" [P]. US Patent, US 10947942 B2, 2025-10-03.
  2. 发明人沈红梅，赵玉洁，孙丽萍. "Method for the Synthesis of 103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-bradykinin" [P]. 中国发明专利, 专利号 CN 108873229 B, 授权公告日 2018-08-10.
  3. 发明人沈红梅，赵玉洁，张德明. "A Process for Preparing High-Purity 103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-bradykinin" [P]. 中国发明专利, 专利号 CN 114800779 B, 授权公告日 2025-06-10.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Biomed. Chromatogr., 2013, 1711, (12), 411-439.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Food Chem., 2018, 966, 9465-9492.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 103412-40-4 B 4310 L-Arginine, N2-(N-(N-(N-(N-(N-(trans-4-hydroxy-1-(1-(N2-(N2-L-lysyl-L-lysyl)-L-arginyl)-L-prolyl)-L-prolyl)glycyl)-3-(2-thienyl)-L-alanyl)-L-seryl)-D-phenylalanyl)-3-(2-thienyl)-L-alanyl)- B-4310 Bradykinin, lys-lys-hyp(3)-(thi-ala)(5,8)-phe(7)- Bradykinin, lys-lys-3-hyp-5,8-thi-7-phe- Bradykinin, lysyl-lysyl-hydroxyproly(3)-(thienylalanyl)(5,8)-phenylalanyl(7)- Lys-lys-3-hyp-5,8-(thi-ala)-7-phe- Lysyl-lysyl-3-(hydroxyprolyl)-5,8-thienyl-7-phenylalanine-bradykinin Using HRMS and NMR". Sci. Total Environ., 2021, 2084, (11), 2342-2357.

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