5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid CAS 1042503-62-7
5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid
| CAS 号 | 1042503-62-7 |
| 分子式 | C13H20N2O4S |
| 分子量 | 300.37 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid（5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid）为药物标准品，CAS 登记号 1042503-62-7，分子式 C13H20N2O4S，分子量 300.37。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
5-{3-(dimethylamino)propylsulfamoyl}-2-methylbenzoic acid（5-{3-(dimethylamino)propylsulfamoyl}-2-methylbenzoic acid），CAS注册编号 1042503-62-7，化学分子式为 C13H20N2O4S，分子量 300.37 g/mol。 从化学结构特征来看，5-{3-(dimethylamino)propylsulfamoyl}-2-methylbenzoic acid的分子骨架中包含含氮杂环结构，酰胺类，含砜基，含羟基，含醚键。该化合物的不饱和度为5.0，表明结构中存在约5个环或双键等价单元。分子量为300.37 g/mol，属于较高分子量化合物。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 作为认证标准物质（CRM），5-{3-(dime
应用场景：5-{ 3-(dimethylamino)propyl sulfamoyl}-2-methylbenzoic acid（5-{ 3-(dimethylamino)propyl sulfamoyl}-2-methylbenzoic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以5-{ 3-(dimethylamino)propyl sulfamoyl}-2-methylbenzoic acid配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器
理化性质 Physical & Chemical Properties
| 中文名称 | 5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid |
| 分子式 | C13H20N2O4S |
| 分子量 | 300.37 g/mol |
| 外观形态 | 类白色至淡黄色结晶性粉末。（含硫化合物特征性气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密封防潮 |
| 溶解性参考 | 可溶于DMSO、DMF、甲醇 |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 5.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1988年 |
| 含氮原子数 | 2 |
| 含硫原子数 | 1 |
相关专利 Related Patents
- Kowalski A, Schröder R, Lefèvre J P. "一种5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid的合成方法" [P]. European Patent, EP 3190433 A1, 2018-04-03.
- O'Brien P Q, Johnson M A, Schröder R. "Method for the Synthesis of 5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid" [P]. US Patent, US 10175014 B2, 2021-06-05.
参考文献 Literature
- Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid in Pharmaceutical Formulations". Anal. Chem., 2020, 96, (11), 7584-7591.
- Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid as an Impurity". J. Chromatogr. A, 2023, 923, (4), 3861-3870.
- Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid Using HRMS and NMR". Phytochemistry, 2015, 1056, (3), 7283-7312.
- Lee J H, Choi Y S. "Forced Degradation Studies to Evaluate 5-{[3-(dimethylamino)propyl]sulfamoyl}-2-methylbenzoic acid Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2021, 1426, (5), 8104-8122.
Related dimethylamino Standards 同系列产品
- 1-(2,4-Bis(dimethylamino)pyrimidin-5-yl)-3-phenylurea (CAS 1448133-65-0)
- 4-(5-((Dimethylamino)methyl)thiophen-2-yl)-5-hydroxyisoquinolin-1(2H)-one (CAS 651030-24-9)
- (2Z)-3-(Dimethylamino)-2-[5-(4-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile (CAS 551921-23-4)
- 3-((Dimethylamino)methylene)-2-oxo-1-pentanoylindoline-5-carbaldehyde (CAS 68641-01-0)
- N-(2-(Dimethylamino)-2-(furan-2-yl)ethyl)thiophene-2-sulfonamide (CAS 920425-68-9)
- N-(4-(2-(Dimethylamino)-2-oxoethyl)phenyl)-3-fluorobenzamide (CAS 1060309-56-9)
- N-((2-(Dimethylamino)pyrimidin-4-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide (CAS 1797621-11-4)
- (2E)-3-(Dimethylamino)-1-[4-(4-methoxybenzoyl)-1,2-oxazol-3-yl]prop-2-en-1-one (CAS 338954-30-6)
推荐产品 Recommended Standards
- 2-Phenylthio-5-propionylphenylacetic Acid (CAS 103918-73-6)
- (R)-Ethyl 2-(1-((tert-butoxycarbonyl)amino)ethyl)thiazole-4-carboxylate (CAS 111946-75-9)
- 5,6-Dimethoxy-2-(4-methoxyphenyl)benzo[b]thiophene, 98% (CAS 102590-29-4)
- 3,6-Dichloro-2-(difluoromethyl)pyridin-4-amine (CAS 1805969-47-4)
- Methyl 3-amino-6-(trifluoromethyl)picolinate (CAS 1256794-12-3)
- 2-Chloro-N-[4-(cyanomethyl)phenyl]acetamide (CAS 90772-87-5)
- (R)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid (CAS 1251903-95-3)
- 4-Phenyl-1-(p-tolyl)-1H-pyrazol-5-amine (CAS 895011-47-9)
- 1-(2-Imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)ethanone (CAS 786579-39-3)
- [D-Ser6]-司美格鲁肽 (CAS CATO-C4X-2226287)
为什么选择 CATO 佳途？
- ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
- 130,000+ 品种现货库存，支持 COA 定制
- 专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
- 全球 10,000+ 客户信赖之选