CAS 108687-08-7

108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride TELUDIPINE HYDROCHLORIDE Taludipine hydrochloride < former INNM Teludipine hydrochloride< Rec INNM

纯度 97%+现货药物标准品
CAS 号108687-08-7
分子式C28H38N2O6
分子量498.61 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride TELUDIPINE HYDROCHLORIDE Taludipine hydrochloride < former INNM Teludipine hydrochloride< Rec INNM CAS 108687-08-7 结构式 Chemical Structure

产品介绍 Description

（英文名 108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride TELUDIPINE HYDROCHLORIDE Taludipine hydrochloride < former INNM Teludipine hydrochloride< Rec INNM，CAS 108687-08-7）属于药物标准品。分子式 C28H38N2O6，分子量 498.61。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 （108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4-2-3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenylphenyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4-o-(E)-2-Carboxyvinylphenyl-2-(dimethylamino)methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride TELUDIPINE HYDROCHLORIDE Taludipine hydrochl

应用场景：（108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4- 2- 3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl phenyl -6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4- o- (E)-2-Carboxyvinyl phenyl -2- (dimethylamino)methyl -6-methyl-1,4

理化性质 Physical & Chemical Properties

中文名称
分子式C28H38N2O6
分子量498.61 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1988年
含氮原子数2

相关专利 Related Patents

  1. Davis P L, Lee S K, Chen K W. "一种的合成方法" [P]. US Patent, US 10941013 B2, 2021-03-04.
  2. Brown S R, Mueller T, Fischer A B. "Method for the Synthesis of 108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride TELUDIPINE HYDROCHLORIDE Taludipine hydrochloride < former INNM Teludipine hydrochloride< Rec INNM" [P]. US Patent, US 11684980 B2, 2024-03-26.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Food Chem., 2018, 1572, (11), 4837-4856.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Methods, 2022, 85, (5), 3830-3845.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of 108687-08-7 BAN D0LN9P Former USAN > GR-53992B GX-1296B Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride TELUDIPINE HYDROCHLORIDE Taludipine hydrochloride < former INNM Teludipine hydrochloride< Rec INNM Using HRMS and NMR". Chemosphere, 2025, 1172, (10), 9655-9658.
  4. O'Brien K, Kennedy M L. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2019, 86, 7822-7840.

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