1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid CAS 1094539-69-1

1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1094539-69-1
分子式C15H20N2O4
分子量292.33 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid CAS 1094539-69-1 结构式 Chemical Structure

产品介绍 Description

1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid（1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid）是药物分析与质量控制领域常用的药物标准品，CAS 号 1094539-69-1。分子式 C15H20N2O4，分子量 292.33。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid（分子式 C15H20N2O4）的化学结构中包含黄酮骨架，酰胺类，含羟基，含醚键。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid（1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid），CAS注册编号 1094539-69-1，化学分子式为 C15H20N2O4，分子量 292.33 g/mol。 推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要

应用场景：1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid（1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1

理化性质 Physical & Chemical Properties

中文名称1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid
分子式C15H20N2O4
分子量292.33 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
含氮原子数2

相关专利 Related Patents

  1. O'Brien P Q, Thompson G K, Chen K W. "一种1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid的合成方法" [P]. US Patent, US 11440315 B2, 2019-12-10.
  2. Klinger H, Fischer A B, Johnson M A. "Method for the Synthesis of 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid" [P]. US Patent, US 9574313 B2, 2020-02-16.
  3. 发明人林芳，朱建伟，郑宇鹏. "A Process for Preparing High-Purity 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid" [P]. 中国发明专利, 专利号 CN 109001728 A, 授权公告日 2023-07-22.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid in Pharmaceutical Formulations". Anal. Methods, 2022, 603, (1), 4757-4766.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid as an Impurity". Phytochemistry, 2014, 2127, (3), 9491-9515.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid Using HRMS and NMR". Chromatographia, 2022, 244, (3), 6151-6162.
  4. Kumar A, Sharma P, Patel R S. "Forced Degradation Studies to Evaluate 1-(1-methyl-2-oxo-1,2-dihydropyridine-4-amido)cycloheptane-1-carboxylic acid Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2012, 2342, 5299-5326.

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