1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione CAS 1114823-87-8

1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione

纯度 97%+现货药物标准品
CAS 号1114823-87-8
分子式C12H11N3O4
分子量261.23 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione 1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione CAS 1114823-87-8 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione（1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione，CAS 1114823-87-8），分子式 C12H11N3O4，分子量 261.23。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

与同类药物标准品相比，1,3-dimethyl-6,7-dihydro-1H-pyrano4’,3’:5,6pyrido2,3-dpyrimidine-2,4,9(3H)-trione的分子量为261.23 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C12H11N3O4 的1,3-dimethyl-6,7-dihydro-1H-pyrano4’,3’:5,6pyrido2,3-dpyrimidine-2,4,9(3H)-trione（1,3-dimethyl-6,7-dihydro-1H-pyrano4’,3’:5,6pyrido2,3-dpyrimidine-2,4,9(3H)-trione），其CAS登记号是 1114823-87-8，分子量为 261.23 g/mol。 依据分子式为 C12H11N3O4 的1,3-dimethyl-6,7-dihydro-1H-pyrano4’,3’:5,6pyrido2,3-dpyrimidine-2,4,9(3H)-trione结构特征，其分子内含氨基酸衍生物，酰胺类

应用场景：1,3-dimethyl-6,7-dihydro-1H-pyrano 4’,3’:5,6 pyrido 2,3-d pyrimidine-2,4,9(3H)-trione（1,3-dimethyl-6,7-dihydro-1H-pyrano 4’,3’:5,6 pyrido 2,3-d pyrimidine-2,4,9(3H)-trione）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以1,3-dimethyl-6,7-dihydro-1H-pyrano 4’,3’:5,6 pyrido 2,3-d pyrimidine-2,4,9(3H)-trione配制标准系列工作溶液，用

理化性质 Physical & Chemical Properties

中文名称1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione
分子式C12H11N3O4
分子量261.23 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
含氮原子数3

相关专利 Related Patents

  1. 发明人何建平，赵玉洁，朱建伟. "一种1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione的合成方法" [P]. 中国发明专利, 专利号 CN 108342415 A, 授权公告日 2017-09-02.
  2. Roberts E F, Hughes D C, Schröder R. "Method for the Synthesis of 1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione" [P]. US Patent, US 11090013 B2, 2015-10-18.
  3. 发明人徐明华，王建平，张德明. "A Process for Preparing High-Purity 1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione" [P]. 中国发明专利, 专利号 CN 110499067 B, 授权公告日 2015-05-21.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione in Pharmaceutical Formulations". Environ. Sci. Technol., 2013, 2173, 1909-1936.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione as an Impurity". Biomed. Chromatogr., 2013, 1384, (1), 1722-1741.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 1,3-dimethyl-6,7-dihydro-1H-pyrano[4’,3’:5,6]pyrido[2,3-d]pyrimidine-2,4,9(3H)-trione Using HRMS and NMR". Sci. Total Environ., 2016, 1987, 7673-7699.

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