6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid CAS 1172878-64-6

6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1172878-64-6
分子式C14H14N4O3
分子量286.29 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid CAS 1172878-64-6 结构式 Chemical Structure

产品介绍 Description

6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid（英文名 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid，CAS 1172878-64-6）属于药物标准品。分子式 C14H14N4O3，分子量 286.29。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo5,4-bpyridine-4-carboxylic acid的分子量为286.29 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo5,4-bpyridine-4-carboxylic acid（6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo5,4-bpyridine-4-carboxylic acid），CAS注册编号 1172878-64-6，化学分子式为 C14H14N4O3，分子量 286.29 g/mol。 从化学结构特征来看，6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo5,4-bpyridine-4-carboxylic acid的分子骨架中包含含氮杂环结构，酰胺类，含羟基，含醚键

应用场景：6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo 5,4-b pyridine-4-carboxylic acid（6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo 5,4-b pyridine-4-carboxylic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo 5,4-b pyridine-4-carboxylic acid配制标准系列工作溶

理化性质 Physical & Chemical Properties

中文名称6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid
分子式C14H14N4O3
分子量286.29 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
含氮原子数4

相关专利 Related Patents

  1. 发明人朱建伟，钱学锋，冯建国. "一种6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid的合成方法" [P]. 中国发明专利, 专利号 CN 110374298 A, 授权公告日 2015-02-24.
  2. 发明人周伟，刘建华，孙丽萍. "Method for the Synthesis of 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid" [P]. 中国发明专利, 专利号 CN 108168214 B, 授权公告日 2022-09-11.
  3. 发明人张德明，郑宇鹏，徐明华. "A Process for Preparing High-Purity 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid" [P]. 中国发明专利, 专利号 CN 110586088 A, 授权公告日 2018-10-25.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid in Pharmaceutical Formulations". J. Chromatogr. A, 2012, 1060, (9), 878-881.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid as an Impurity". Molecules, 2015, 1450, (7), 1244-1248.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of 6-methyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid Using HRMS and NMR". Phytochemistry, 2016, 706, (3), 7033-7036.

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