CAS 1245916-14-6

1245916-14-6 PP0SHH6V16 Alirocumab [USAN:INN] REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSDB 8280

纯度 97%+现货药物标准品
CAS 号1245916-14-6
分子式C3H9O6P 2*Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1245916-14-6 PP0SHH6V16 Alirocumab [USAN:INN] REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSDB 8280 CAS 1245916-14-6 结构式 Chemical Structure

产品介绍 Description

CAS 1245916-14-6 对应的（1245916-14-6 PP0SHH6V16 Alirocumab [USAN:INN] REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSDB 8280）为 CATO 佳途药物标准品产品线成员。分子式 C3H9O6P 2*Na。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

与同类药物标准品相比，的分子量为195.06 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 （1245916-14-6 PP0SHH6V16 Alirocumab USAN:INN REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSDB 8280），CAS注册编号 1245916-14-6，化学分子式为 C3H9O6P 2Na，分子量 195.06 g/mol。 （C3H9O6P 2Na）含有含磷酸酯基，羧酸类，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳

应用场景：（1245916-14-6 PP0SHH6V16 Alirocumab USAN:INN REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSD

理化性质 Physical & Chemical Properties

中文名称
分子式C3H9O6P 2*Na
分子量195.06 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-0.5
CAS登记年份（估）1990年

相关专利 Related Patents

  1. 发明人张德明，罗永刚，刘建华. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 114078143 B, 授权公告日 2024-08-02.
  2. 发明人林芳，沈红梅，李文辉. "Method for the Synthesis of 1245916-14-6 PP0SHH6V16 Alirocumab [USAN:INN] REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSDB 8280" [P]. 中国发明专利, 专利号 CN 112455975 B, 授权公告日 2024-12-05.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Sci. Total Environ., 2020, 1791, (7), 7279-7284.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Chem., 2018, 2385, (1), 2761-2779.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 1245916-14-6 PP0SHH6V16 Alirocumab [USAN:INN] REGN727 monoclonal antibody Alirocumab Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human REGN727 heavy chain), disulfide with human REGN727 kapa-chain, dimer UNII-PP0SHH6V16 REGN 727 SAR 236553 REGN727 SAR236553 Praluent HSDB 8280 Using HRMS and NMR". J. Agric. Food Chem., 2018, 1062, 6314-6327.
  4. Lee J H, Choi Y S. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2022, 2146, (5), 6538-6545.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...