Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester CAS 1259933-02-2
Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester
| CAS 号 | 1259933-02-2 |
| 分子式 | C19H28O5 |
| 分子量 | 336.42 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CAS 1259933-02-2 对应的Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester（Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester）为 CATO 佳途药物标准品产品线成员。分子式 C19H28O5，分子量 336.42。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。
Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-(1S)-4-hydroxy-1-methylbutyl-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester（Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-(1S)-4-hydroxy-1-methylbutyl-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester），CAS注册编号 1259933-02-2，化学分子式为 C19H28O5，分子量 336.42 g/mol。 受分子结构中甾体骨架，含羟基，含醚键的影响，Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-(1S)-4-hydroxy-1-methylbutyl-6-methyl-3-methylene-2-oxo-4-benzo
应用场景：针对化学分析用途，Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5- (1S)-4-hydroxy-1-methylbutyl -6-methyl-3-methylene-2-oxo-4-benzofuranyl ester（Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5- (1S)-4-hydroxy-1-methylbutyl -6-methyl-3-methylene-2-oxo-4-benzofuranyl ester）是
理化性质 Physical & Chemical Properties
| 中文名称 | Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester |
| 分子式 | C19H28O5 |
| 分子量 | 336.42 g/mol |
| 外观形态 | 类白色至淡黄色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 6.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1990年 |
相关专利 Related Patents
- 发明人陈志强，张德明，郭海燕. "一种Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester的合成方法" [P]. 中国发明专利, 专利号 CN 116866905 A, 授权公告日 2025-08-18.
- 发明人高志强，冯建国，赵玉洁. "Method for the Synthesis of Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester" [P]. 中国发明专利, 专利号 CN 115628438 A, 授权公告日 2018-11-06.
参考文献 Literature
- Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester in Pharmaceutical Formulations". J. Agric. Food Chem., 2010, 1291, (1), 9469-9492.
- Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester as an Impurity". Biomed. Chromatogr., 2012, 110, (6), 6395-6399.
- Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester Using HRMS and NMR". Talanta, 2018, 1011, 5418-5437.
- Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate Propanoic acid, 2-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester Profile in Drug Substances According to ICH Guidelines". Molecules, 2025, 1526, (11), 4945-4954.
Related Propanoic Standards 同系列产品
- Propanoic acid, 3-[[bis(2-methylpropoxy)phosphinothioyl]thio]-2-methyl- (CAS 268567-32-4)
- 59979-57-6 Propanoic acid,2-methyl-,(3aR,4R,6R,9R,10Z,11aR)-2,3,3a,4,5,6,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-ylester (CAS 59979-57-6)
- Propanoic acid, 2-[[(butylthio)thioxomethyl]thio]-2-methyl-, 2,5-dioxo-1-pyrrolidinyl ester (CAS 1268691-68-4)
- Propanoic acid, 2-bromo-2-methyl-, 2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,1-dimethyl-2-oxoethyl ester (CAS 1431509-31-7)
- 2-[4-(4-氰基-2-氟苯氧基)苯氧基]-丙酸丁酯 (CAS 122008-82-6)
- Propanoic acid, 2,2-dimethyl-, 3-[(1R,2R)-2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]cyclopropyl]-4-hydroxyphenyl esteR, rel- (CAS 1322699-95-5)
- 110382-37-1 Propanoic acid,2-methyl-,2,3,3a,4,5,6,9,11b-octahydro-9-methoxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-ylester, [3aR-(3aR*,4R*,6R*,9R*,10Z,11aR*)]- (9CI) (CAS 110382-37-1)
- Propanoic acid, 2,2-dimethyl-, [[(4-nitrophenoxy)carbonyl]oxy]methyl ester (CAS 101623-83-0)
推荐产品 Recommended Standards
- 溶剂橙 63 (CAS 16294-75-0)
- N/A (CAS 146395-16-6)
- 阿莫曲坦杂质8 (CAS CATO-C4X-15388)
- 1-Amino-3-(4-methyl-1h-pyrazol-1-yl)cyclopentane-1-carboxamide (CAS 1526816-33-0)
- Tert-butyl3-allyl-3-(hydroxymethyl)piperidine-1-carboxylate (CAS 441773-93-9)
- (5-chloro-1-methyl-1H-imidazol-2-yl)methanamine dihydrochloride (CAS 1820648-72-3)
- 2-(1H-Imidazol-2-yl)benzonitrile (CAS 204078-65-9)
- Tert-butyl (2-methoxyphenyl)glycinate (CAS 139088-94-1)
- 利那洛肽杂质41 (CAS CATO-C4X-210641)
- Des-Ile17-替尔泊肽 (CAS CATO-CPTD788956)
为什么选择 CATO 佳途？
- ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
- 130,000+ 品种现货库存，支持 COA 定制
- 专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
- 全球 10,000+ 客户信赖之选