CAS 126602-89-9

126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-((2S)-5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-2-piperidinecarboxylic acid-, mixt. with (3R,4R,5E,10E,12E,14S26R,26aS)-26-((2-(diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone RP-59500 Synercid Dalfopristin - quinupristin mixt. Quinupristin - dalfopristin mixt Dalfopristin mixture with Quinupristin Quinupristin and dalfopristin RP 59500

纯度 97%+现货药物标准品
CAS 号126602-89-9
分子式C53H67N9O10S C34H50N4O9S
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-((2S)-5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-2-piperidinecarboxylic acid-, mixt. with (3R,4R,5E,10E,12E,14S26R,26aS)-26-((2-(diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone RP-59500 Synercid Dalfopristin - quinupristin mixt. Quinupristin - dalfopristin mixt Dalfopristin mixture with Quinupristin Quinupristin and dalfopristin RP 59500 CAS 126602-89-9 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品（126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-((2S)-5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-2-piperidinecarboxylic acid-, mixt. with (3R,4R,5E,10E,12E,14S26R,26aS)-26-((2-(diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone RP-59500 Synercid Dalfopristin - quinupristin mixt. Quinupristin - dalfopristin mixt Dalfopristin mixture with Quinupristin Quinupristin and dalfopristin RP 59500，CAS 126602-89-9），分子式 C53H67N9O10S C34H50N4O9S。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 CAS编号 126602-89-9 对应的化合物（英文标识 126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-((2S)-5-((1-azabicyclo(2.2.2)oct-3-ylthio)me

应用场景：（126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-

理化性质 Physical & Chemical Properties

中文名称
分子式C53H67N9O10S C34H50N4O9S
分子量1713.08 g/mol
外观形态淡黄色至黄色无定形粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）36.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1993年
含氮原子数13
含硫原子数2

相关专利 Related Patents

  1. Roberts E F, Park J H, Fischer A B. "一种的合成方法" [P]. US Patent, US 10954962 B2, 2024-09-10.
  2. 发明人马晓峰，郑宇鹏，张德明. "Method for the Synthesis of 126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-((2S)-5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-2-piperidinecarboxylic acid-, mixt. with (3R,4R,5E,10E,12E,14S26R,26aS)-26-((2-(diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone RP-59500 Synercid Dalfopristin - quinupristin mixt. Quinupristin - dalfopristin mixt Dalfopristin mixture with Quinupristin Quinupristin and dalfopristin RP 59500" [P]. 中国发明专利, 专利号 CN 113081450 B, 授权公告日 2025-01-03.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Environ. Sci. Technol., 2018, 294, 5230-5252.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Food Chem., 2018, 910, (1), 8677-8682.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 126602-89-9 Quinupristin-dalfopristin Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, mixt. with 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)virginiamycin S1 Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-((2S)-5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-2-piperidinecarboxylic acid-, mixt. with (3R,4R,5E,10E,12E,14S26R,26aS)-26-((2-(diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone RP-59500 Synercid Dalfopristin - quinupristin mixt. Quinupristin - dalfopristin mixt Dalfopristin mixture with Quinupristin Quinupristin and dalfopristin RP 59500 Using HRMS and NMR". Phytochemistry, 2020, 659, (3), 4543-4568.

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