CAS 127243-65-6

.beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2-[(1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate) 127243-65-6 Woodfordin A [(2S,3R,4S,5R,6R)-5-hydroxy-2,4-bis[(3,4,5-trihydroxybenzoyl)oxy]-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]tetrahydropyran-3-yl] 3,4,5-trihydroxy-2-[pentahydroxy-dioxo-tris[(3,4,5-trihydroxybenzoyl)oxy][?]yl]oxy-benzoate

纯度 97%+现货药物标准品
CAS 号127243-65-6
分子式C75H56O48
分子量1725.22 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

 .beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2-[(1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate)
127243-65-6
Woodfordin A
[(2S,3R,4S,5R,6R)-5-hydroxy-2,4-bis[(3,4,5-trihydroxybenzoyl)oxy]-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]tetrahydropyran-3-yl] 3,4,5-trihydroxy-2-[pentahydroxy-dioxo-tris[(3,4,5-trihydroxybenzoyl)oxy][?]yl]oxy-benzoate CAS 127243-65-6 结构式 Chemical Structure

产品介绍 Description

(.beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2-[(1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate) 127243-65-6 Woodfordin A [(2S,3R,4S,5R,6R)-5-hydroxy-2,4-bis[(3,4,5-trihydroxybenzoyl)oxy]-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]tetrahydropyran-3-yl] 3,4,5-trihydroxy-2-[pentahydroxy-dioxo-tris[(3,4,5-trihydroxybenzoyl)oxy][?]yl]oxy-benzoate,CAS 号 127243-65-6)是 CATO 佳途自主生产的药物标准品,分子式 C75H56O48,分子量 1725.22。纯度 97%+。本品采用严格的质量控制体系生产,附 COA 证书,适用于药物研发、质量控制和法规申报等场景。

在定量分析中,可作为校准标准或内标物使用,适用于多种检测技术平台(UV-Vis, FLD, MS, FID)。 CAS编号 127243-65-6 对应的化合物(英文标识 .beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2-(1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy1,1'-biphenyl-2,2'-dicarboxylate 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate) 127243-65-6 Woodfordin A (2S,3R,4S,5R,6R)-5-hydroxy-2,4-bis(3,4,5-trihydroxybenzoyl)oxy-6-(3,4,5-trihydroxybenzoyl)oxymethyltetrah

应用场景:(.beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2- (1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy 1,1'-biphenyl -2,2'-dicarboxylate 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate) 127243-65-6 Woodfordin A (2S

理化性质 Physical & Chemical Properties

中文名称
分子式C75H56O48
分子量1725.22 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件室温保存,避光,密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水(微溶)
稳定性空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)48.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份(估)1993年

相关专利 Related Patents

  1. Sørensen M, Johansson L, Rossi M. "一种的合成方法" [P]. European Patent, EP 3889347 A1, 2025-07-27.
  2. 发明人韩伟,罗永刚,徐明华. "Method for the Synthesis of .beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2-[(1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate) 127243-65-6 Woodfordin A [(2S,3R,4S,5R,6R)-5-hydroxy-2,4-bis[(3,4,5-trihydroxybenzoyl)oxy]-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]tetrahydropyran-3-yl] 3,4,5-trihydroxy-2-[pentahydroxy-dioxo-tris[(3,4,5-trihydroxybenzoyl)oxy][?]yl]oxy-benzoate" [P]. 中国发明专利, 专利号 CN 108457085 A, 授权公告日 2015-01-26.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Biomed. Chromatogr., 2024, 891, 8284-8294.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". J. Sep. Sci., 2015, 1305, (1), 3150-3173.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of .beta.-D-Glucopyranose, cyclic 4.fwdarw.2':6.fwdarw.2-[(1S)-4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1,2,3-tris(3,4,5-trihydroxybenzoate), 2-ester with .beta.-D-glucopyranose 1,3,6-tris(3,4,5-trihydroxybenzoate) 127243-65-6 Woodfordin A [(2S,3R,4S,5R,6R)-5-hydroxy-2,4-bis[(3,4,5-trihydroxybenzoyl)oxy]-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]tetrahydropyran-3-yl] 3,4,5-trihydroxy-2-[pentahydroxy-dioxo-tris[(3,4,5-trihydroxybenzoyl)oxy][?]yl]oxy-benzoate Using HRMS and NMR". J. Chromatogr. A, 2014, 933, (5), 1559-1587.

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