[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid CAS 1291949-42-2

[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid

纯度 97%+现货药物标准品
CAS 号1291949-42-2
分子式C12H14N2O4S
分子量282.32 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid CAS 1291949-42-2 结构式 Chemical Structure

产品介绍 Description

[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid（[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid，CAS 号 1291949-42-2）是 CATO 佳途自主生产的药物标准品，分子式 C12H14N2O4S，分子量 282.32。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

CAS编号 1291949-42-2 对应的化合物(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno2,3-dpyrimidin-2-yl)methoxyacetic acid（英文标识 (5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno2,3-dpyrimidin-2-yl)methoxyacetic acid），化学式 C12H14N2O4S，相对分子质量 282.32。 从化学结构特征来看，(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno2,3-dpyrimidin-2-yl)methoxyacetic acid的分子骨架中包含含氮杂环结构，酰胺类，含砜基，含羟基，含醚键。该化合物的不饱和度为7.0，表明结构中存在约7个环或双键等价单元。分子量为282.32 g/mol，属于中等分子量化合物。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 本品适用于HPLC、GC、LC-MS/MS、G

应用场景： (5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno 2,3-d pyrimidin-2-yl)methoxy acetic acid（ (5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno 2,3-d pyrimidin-2-yl)methoxy acetic acid，CAS 1291949-42-2）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以 (5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno 2,3-d pyrimidin-2-yl)methoxy acetic acid配制标

理化性质 Physical & Chemical Properties

中文名称[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid
分子式C12H14N2O4S
分子量282.32 g/mol
外观形态类白色至淡黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. Sørensen M, Martínez F, Schröder R. "一种[(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid的合成方法" [P]. European Patent, EP 3577564 A1, 2017-09-23.
  2. 发明人钱学锋，郑宇鹏，朱建伟. "Method for the Synthesis of [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid" [P]. 中国发明专利, 专利号 CN 110182478 A, 授权公告日 2017-09-12.
  3. Kowalski A, Jørgensen K, Björnsson E. "A Process for Preparing High-Purity [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid" [P]. European Patent, EP 3240430 A1, 2025-08-10.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid in Pharmaceutical Formulations". Environ. Sci. Technol., 2014, 83, (7), 9558-9574.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid as an Impurity". J. Pharm. Biomed. Anal., 2013, 2098, 2910-2940.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid Using HRMS and NMR". J. Nat. Prod., 2016, 1774, 8712-8718.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate [(5-ethyl-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methoxy]acetic acid Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2023, 111, 5995-6004.

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