5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)- CAS 1301267-02-6

5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-

纯度 97%+现货药物标准品
CAS 号1301267-02-6
分子式C32H52O4
分子量500.75 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)- 5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)- CAS 1301267-02-6 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-（5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-）为药物标准品，CAS 登记号 1301267-02-6，分子式 C32H52O4，分子量 500.75。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括5,9-(Epoxymethano)-2H-cyclopentaaphenanthren-3-ol, 20-ethoxy-17-(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-在内的目标物的控制。 化学式为 C32H52O4 的5,9-(Epoxymethano)-2H-cyclopentaaphenanthren-3-ol, 20-ethoxy-17-(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-（5,9-(Epoxymeth

应用场景：从实际应用出发，5,9-(Epoxymethano)-2H-cyclopenta a phenanthren-3-ol, 20-ethoxy-17- (1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl -1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-（CAS 1301267-02-6）在化学分析中作为关键的基准对照物质。 推荐以5,9-(Epoxymethano)-2H-cyclopenta a ph

理化性质 Physical & Chemical Properties

中文名称5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-
分子式C32H52O4
分子量500.75 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年

相关专利 Related Patents

  1. Davis P L, Patel M V, Brown S R. "一种5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-的合成方法" [P]. US Patent, US 9218084 B2, 2017-05-07.
  2. 发明人赵玉洁，唐晓军，郭海燕. "Method for the Synthesis of 5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)-" [P]. 中国发明专利, 专利号 CN 116727440 A, 授权公告日 2016-01-03.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)- in Pharmaceutical Formulations". Anal. Methods, 2022, 2213, 8092-8102.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-3-ol, 20-ethoxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R,20R)- as an Impurity". Chemosphere, 2016, 144, (7), 7785-7801.

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