1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride CAS 1311315-99-7

1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride

纯度 97%+现货药物标准品
CAS 号1311315-99-7
分子式C16H20N4O3 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride 1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride CAS 1311315-99-7 结构式 Chemical Structure

产品介绍 Description

CAS 1311315-99-7 对应的1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride（1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride）为 CATO 佳途药物标准品产品线成员。分子式 C16H20N4O3 2*HCl。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

依据分子式为 C16H20N4O3 2HCl 的1-2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride结构特征，其分子内含含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 352.82 g/mol 这一参数对质谱检测中的分子离子峰识别具有直接参考价值。分子中的氮原子赋予该化合物一定的碱性特征，在酸性流动相条件下可被有效质子化。 1-2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride（1-2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl-5-methyl-1H-1,2,3-triazole-4-carboxyl

应用场景：1- 2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl -5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride（1- 2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl -5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride，CAS 1311315-99-7）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以1- 2-(2-methoxye

理化性质 Physical & Chemical Properties

中文名称1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride
分子式C16H20N4O3 2*HCl
分子量352.82 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. Jørgensen K, Lefèvre J P, Kowalski A. "一种1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride的合成方法" [P]. European Patent, EP 3057112 A1, 2016-10-17.
  2. 发明人陈志强，沈红梅，李文辉. "Method for the Synthesis of 1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride" [P]. 中国发明专利, 专利号 CN 112609237 B, 授权公告日 2019-01-01.
  3. Anderson J P, Chen K W, Fischer A B. "A Process for Preparing High-Purity 1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride" [P]. US Patent, US 10890939 B2, 2018-07-25.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride in Pharmaceutical Formulations". J. Nat. Prod., 2022, 717, (12), 8701-8710.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride as an Impurity". Anal. Chim. Acta, 2011, 599, (4), 9390-9413.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 1-[2-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid dihydrochloride Using HRMS and NMR". Molecules, 2011, 2057, (9), 9989-10017.

Related methoxyethyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...