3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride CAS 1326743-66-1

3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride

纯度 97%+现货药物标准品
CAS 号1326743-66-1
分子式C13H21N5O 3*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride 3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride CAS 1326743-66-1 结构式 Chemical Structure

产品介绍 Description

3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride（英文名 3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride，CAS 1326743-66-1）属于药物标准品。分子式 C13H21N5O 3*HCl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

化学式为 C13H21N5O 3HCl 的3-amino-1-{3,5,6,7-tetrahydrospiroimidazo4,5-cpyridine-4,4’-piperidine-1’-yl}propan-1-one trihydrochloride（3-amino-1-{3,5,6,7-tetrahydrospiroimidazo4,5-cpyridine-4,4’-piperidine-1’-yl}propan-1-one trihydrochloride），其CAS登记号是 1326743-66-1，分子量为 299.80 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代的影响，3-amino-1-{3,5,6,7-tetrahydrospiroimidazo4,5-cpyridine-4,4’-piperidine-1’-yl}propan-1-one trihydrochloride表现为类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）。其固体形态的物理化学属性——包括299.80 g/mol的分子量——对于选择合适

应用场景：3-amino-1-{3,5,6,7-tetrahydrospiro imidazo 4,5-c pyridine-4,4’-piperidine -1’-yl}propan-1-one trihydrochloride（3-amino-1-{3,5,6,7-tetrahydrospiro imidazo 4,5-c pyridine-4,4’-piperidine -1’-yl}propan-1-one trihydrochloride，CAS 1326743-66-1）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以3-amino-1-{3,5,6,7-tetrahydrospi

理化性质 Physical & Chemical Properties

中文名称3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride
分子式C13H21N5O 3*HCl
分子量299.80 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1991年
卤素含量Cl取代
含氮原子数5

相关专利 Related Patents

  1. 发明人冯建国，张德明，李文辉. "一种3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 108178491 A, 授权公告日 2021-12-18.
  2. Kumar R, Fischer A B, Mueller T. "Method for the Synthesis of 3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride" [P]. US Patent, US 9753157 B2, 2023-06-15.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride in Pharmaceutical Formulations". Talanta, 2017, 1162, (1), 7855-7861.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride as an Impurity". Phytochemistry, 2019, 1144, (11), 1192-1220.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 3-amino-1-{3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-piperidine]-1’-yl}propan-1-one trihydrochloride Using HRMS and NMR". Food Chem., 2019, 1271, (7), 6165-6190.

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