Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) CAS 1388712-91-1

Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)

纯度 97%+现货药物标准品
CAS 号1388712-91-1
分子式C20H21N2P C18H15P Cl2Ru
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) CAS 1388712-91-1 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)（Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)）为药物标准品，CAS 登记号 1388712-91-1，分子式 C20H21N2P C18H15P Cl2Ru。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

Dichlorotriphenylphosphine2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamineruthenium(II)（Dichlorotriphenylphosphine2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamineruthenium(II)），CAS注册编号 1388712-91-1，化学分子式为 C20H21N2P C18H15P Cl2Ru，分子量 754.64 g/mol。 Dichlorotriphenylphosphine2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamineruthenium(II)（分子式 C20H21N2P C18H15P Cl2Ru）的化学结构中包含含氮杂环结构，含氰基，有机磷，含氯取代。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。含

应用场景：在化学分析实验室中，Dichlorotriphenylphosphine 2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine ruthenium(II)（CAS 1388712-91-1）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以Dichlorotriphenylphosphine 2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine ruthenium(II)配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶

理化性质 Physical & Chemical Properties

中文名称Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)
分子式C20H21N2P C18H15P Cl2Ru
分子量754.64 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）21.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1991年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人冯建国，钱学锋，郭海燕. "一种Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)的合成方法" [P]. 中国发明专利, 专利号 CN 111201784 B, 授权公告日 2016-06-13.
  2. 发明人何建平，杨光，孙丽萍. "Method for the Synthesis of Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)" [P]. 中国发明专利, 专利号 CN 111841601 B, 授权公告日 2024-10-22.
  3. 发明人沈红梅，罗永刚，韩伟. "A Process for Preparing High-Purity Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II)" [P]. 中国发明专利, 专利号 CN 112565675 A, 授权公告日 2023-06-17.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) in Pharmaceutical Formulations". Molecules, 2012, 2321, 3645-3658.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) as an Impurity". Biomed. Chromatogr., 2019, 425, 6407-6420.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) Using HRMS and NMR". J. Chromatogr. A, 2017, 1921, (9), 136-151.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate Dichlorotriphenylphosphine[2-(diphenylphosphino)-<I>N</I>-(2-pyridinylmethyl)ethanamine]ruthenium(II) Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2010, 1420, (5), 7219-7227.

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