(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine CAS 1388894-05-0

(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine

纯度 97%+现货药物标准品
CAS 号1388894-05-0
分子式C17H25ClN2OSSi
分子量369.00 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine (R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine CAS 1388894-05-0 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine（(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine，CAS 1388894-05-0），分子式 C17H25ClN2OSSi，分子量 369.00。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta4,5Thieno2,3-DPyrimidine的产生途径与其化学式中甾体骨架，酰胺类，含硫有机，含羟基，含醚键，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 (R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta4,5Thieno2,3-DPyrimidine（(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta4,5Thieno2,3-DPyrimidine），CAS注册编号 1388894-05-0，化学分子式为 C17H25ClN2OSSi，分子量 369.00 g/mol。 (R)-5-(2-((Tert-Butyldimethylsilyl)Ox

应用场景：针对化学分析用途，(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta 4,5 Thieno 2,3-D Pyrimidine（(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta 4,5 Thieno 2,3-D Pyrimidine）是具有明确定量溯源的认证级对照品。 推荐以(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chl

理化性质 Physical & Chemical Properties

中文名称(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine
分子式C17H25ClN2OSSi
分子量369.00 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1991年
卤素含量Cl取代
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. Lefèvre J P, Johansson L, Björnsson E. "一种(R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine的合成方法" [P]. European Patent, EP 3966796 A1, 2016-11-02.
  2. Thompson G K, Johnson M A, Anderson J P. "Method for the Synthesis of (R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine" [P]. US Patent, US 9463526 B2, 2017-05-26.
  3. 发明人刘建华，高志强，唐晓军. "A Process for Preparing High-Purity (R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine" [P]. 中国发明专利, 专利号 CN 111571242 A, 授权公告日 2020-01-14.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of (R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine in Pharmaceutical Formulations". J. Agric. Food Chem., 2010, 1968, (7), 1598-1623.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of (R)-5-(2-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine as an Impurity". J. Pharm. Biomed. Anal., 2019, 1624, (6), 8567-8581.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...