CAS 139059-00-0

(4R-5R)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarboxylate

纯度 97%+现货药物标准品
CAS 号139059-00-0
分子式C19H19NO5S
分子量373.42 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(4R-5R)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarboxylate CAS 139059-00-0 结构式 Chemical Structure

产品介绍 Description

（(4R-5R)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarboxylate）是药物分析与质量控制领域常用的药物标准品，CAS 号 139059-00-0。分子式 C19H19NO5S，分子量 373.42。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在质量保证方面，的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 CAS编号 139059-00-0 对应的化合物（英文标识 (4R-5R)-4,5-Dihydro-5-4-(methylsulfonyl)phenyl-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5-4-(methylsulfonyl)phenyl-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarboxylate），化学式 C19H19NO5S，相对分子质量 373.42。

应用场景：针对化学分析用途，（(4R-5R)-4,5-Dihydro-5- 4-(methylsulfonyl)phenyl -2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5- 4-(methylsulfonyl)phenyl -2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarbox

理化性质 Physical & Chemical Properties

中文名称
分子式C19H19NO5S
分子量373.42 g/mol
外观形态淡黄色至黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1996年
含氮原子数1
含硫原子数1

相关专利 Related Patents

  1. 发明人杨光，陈志强，沈红梅. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 113625352 B, 授权公告日 2023-12-13.
  2. Davis P L, Stevens L M, Roberts E F. "Method for the Synthesis of (4R-5R)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarboxylate" [P]. US Patent, US 11675901 B2, 2020-02-24.
  3. Johnson M A, Roberts E F, Stevens L M. "A Process for Preparing High-Purity (4R-5R)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester (4R-cis)-4,5-Dihydro-5-[4-(methylsulfonyl)phenyl]-2-phenyl-4-oxazolecarboxylic Acid Ethyl Ester 139059-00-0 Ethyl (4R,5R)-D-erythro-4,5-Dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolecarboxylate" [P]. US Patent, US 10345940 B2, 2017-07-11.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Chromatographia, 2019, 2221, 5198-5221.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Talanta, 2010, 354, (1), 9230-9257.

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