Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate CAS 1422343-85-8

Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate

纯度 97%+现货药物标准品
CAS 号1422343-85-8
分子式C13H24N2O4
分子量272.34 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate CAS 1422343-85-8 结构式 Chemical Structure

产品介绍 Description

Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate（英文名 Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate，CAS 1422343-85-8）属于药物标准品。分子式 C13H24N2O4，分子量 272.34。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

作为认证标准物质（CRM），Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo2,1-C1,4Oxazin-7-Yl)Carbamate满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo2,1-C1,4Oxazin-7-Yl)Carbamate（Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo2,1-C1,4Oxazin-7-Yl)Carbamate），CAS注册编号 1422343-85-8，化学分子式为 C13H24N2O4，分子量 272.34 g/mol。 受分子结构中酰胺类，羧酸类，含羟基，含醚键的影响，Race

应用场景：针对化学分析用途，Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo 2,1-C 1,4 Oxazin-7-Yl)Carbamate（Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo 2,1-C 1,4 Oxazin-7-Yl)Carbamate）是具有明确定量溯源的认证级对照品。 推荐以Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo

理化性质 Physical & Chemical Properties

中文名称Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate
分子式C13H24N2O4
分子量272.34 g/mol
外观形态白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1991年
含氮原子数2

相关专利 Related Patents

  1. 发明人朱建伟，刘建华，王建平. "一种Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate的合成方法" [P]. 中国发明专利, 专利号 CN 109653960 A, 授权公告日 2020-07-04.
  2. 发明人郑宇鹏，沈红梅，钱学锋. "Method for the Synthesis of Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate" [P]. 中国发明专利, 专利号 CN 108111908 A, 授权公告日 2023-02-09.
  3. Kowalski A, Jørgensen K, Martínez F. "A Process for Preparing High-Purity Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate" [P]. European Patent, EP 3811756 A1, 2023-06-12.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate in Pharmaceutical Formulations". Anal. Chim. Acta, 2015, 161, (10), 1063-1068.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate as an Impurity". J. Chromatogr. A, 2017, 1976, (7), 2811-2832.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of Racemic-Tert-Butyl ((7R,8S)-8-Hydroxy-8A-Methylhexahydro-1H-Pyrrolo[2,1-C][1,4]Oxazin-7-Yl)Carbamate Using HRMS and NMR". Environ. Sci. Technol., 2015, 2017, (9), 2181-2209.

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