(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride CAS 1432679-11-2

(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1432679-11-2
分子式C7H12N4 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride CAS 1432679-11-2 结构式 Chemical Structure

产品介绍 Description

CAS 1432679-11-2 对应的(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride（(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride）为 CATO 佳途药物标准品产品线成员。分子式 C7H12N4 2*HCl。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride的产生途径与其化学式中含氰基，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C7H12N4 2HCl 的(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride（(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride），其CAS登记号是 1432679-11-2，分子量为 188.66 g/mol。 受分子结构中含氰基，含氯取代的影响，(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride表现为白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）。其固体形态的物理化学属性——包括188.66 g/mol的

应用场景：在化学分析实验室中，(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride（CAS 1432679-11-2）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30

理化性质 Physical & Chemical Properties

中文名称(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride
分子式C7H12N4 2*HCl
分子量188.66 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1991年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. Hughes D C, Park J H, Williams B T. "一种(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride的合成方法" [P]. US Patent, US 10193839 B2, 2024-03-25.
  2. Davis P L, Williams B T, Anderson J P. "Method for the Synthesis of (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride" [P]. US Patent, US 10696447 B2, 2019-09-08.
  3. Rossi M, Johansson L, Sørensen M. "A Process for Preparing High-Purity (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride" [P]. European Patent, EP 3827711 A1, 2015-05-15.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride in Pharmaceutical Formulations". Sci. Total Environ., 2015, 1329, 7853-7857.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride as an Impurity". Molecules, 2020, 1919, 5043-5070.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride Using HRMS and NMR". J. Agric. Food Chem., 2023, 2037, (5), 6890-6911.

Related cyclopropyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...