CAS 143724-76-9

143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin Tri-O-methoxymethyl Ether Noranhydroicaritin Tri-O-methoxymethyl Ether

纯度 97%+现货药物标准品
CAS 号143724-76-9
分子式C26H30O9
分子量486.51 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin Tri-O-methoxymethyl Ether Noranhydroicaritin Tri-O-methoxymethyl Ether CAS 143724-76-9 结构式 Chemical Structure

产品介绍 Description

（英文名 143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin Tri-O-methoxymethyl Ether Noranhydroicaritin Tri-O-methoxymethyl Ether，CAS 143724-76-9）属于药物标准品。分子式 C26H30O9，分子量 486.51。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

受分子结构中羧酸类，含羟基，含醚键，多环芳烃的影响，表现为淡黄色至黄色结晶性粉末。其固体形态的物理化学属性——包括486.51 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 （143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin

应用场景：从实际应用出发，（CAS 143724-76-9）在化学分析中作为关键的基准对照物质。 推荐以配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于室温保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称
分子式C26H30O9
分子量486.51 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）12.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1998年

相关专利 Related Patents

  1. 发明人钱学锋，韩伟，林芳. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 110511586 B, 授权公告日 2022-03-09.
  2. Fischer A B, Stevens L M, Roberts E F. "Method for the Synthesis of 143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin Tri-O-methoxymethyl Ether Noranhydroicaritin Tri-O-methoxymethyl Ether" [P]. US Patent, US 10934328 B2, 2016-09-11.
  3. 发明人马晓峰，罗永刚，何建平. "A Process for Preparing High-Purity 143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin Tri-O-methoxymethyl Ether Noranhydroicaritin Tri-O-methoxymethyl Ether" [P]. 中国发明专利, 专利号 CN 116383124 A, 授权公告日 2016-12-12.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Chromatogr. A, 2024, 2302, (5), 2328-2353.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Methods, 2014, 1664, 8939-8958.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 143724-76-9 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4'-Desmethylicaritin Tri-O-methoxymethyl Ether 8-Prenylkaempferol Tri-O-methoxymethyl Ether De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether Desmethyl Icaritin Tri-O-methoxymethyl Ether Noranhydroicaritin Tri-O-methoxymethyl Ether Using HRMS and NMR". Anal. Chem., 2024, 2128, (2), 8999-9013.

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