(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环) CAS 149820-65-5

(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy)]bis[(6-methoxy-4-quinolyl)methylene]]bis(3-ethylquinuclidine)

纯度 97%+现货药物标准品
CAS 号149820-65-5
分子式C56H60N6O4
分子量881.11 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环) (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy)]bis[(6-methoxy-4-quinolyl)methylene]]bis(3-ethylquinuclidine) CAS 149820-65-5 结构式 Chemical Structure

产品介绍 Description

(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环)（英文名 (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy)]bis[(6-methoxy-4-quinolyl)methylene]]bis(3-ethylquinuclidine)，CAS 149820-65-5）属于药物标准品。分子式 C56H60N6O4，分子量 881.11。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-(1R,1’R)-(2,5-二苯基嘧啶-4,6-二基)双(氧基)双(6-甲氧基-4-喹啉基)亚甲基双(3-乙基奎宁环)在内的目标物的控制。 (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-(1R,1’R)-(2,5-二苯基嘧啶-4,6-二基)双(氧基)双(6-甲氧基-4-喹啉基)亚甲基双(3-乙基奎宁环)（(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-(1R,1’R)-(2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy)bis(6-methoxy-4-quinolyl)methylenebis(3-ethylquinuclidine)），CAS注册编号 149820-65-5，化学分子式为 C56H60N6O4，分子量 881.11 g/mol。 从化学结构特征来看，(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-(1R

应用场景：(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’- (1R,1’R)- (2,5-二苯基嘧啶-4,6-二基)双(氧基) 双 (6-甲氧基-4-喹啉基)亚甲基 双(3-乙基奎宁环)（(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’- (1R,1’R)- (2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy) bis (6-methoxy-4-quinolyl)methylene bis(3-ethylquinuclidine)）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以(1S,1’S,3R,3’R,4S,

理化性质 Physical & Chemical Properties

中文名称(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环)
分子式C56H60N6O4
分子量881.11 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）30.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1999年
含氮原子数6

相关专利 Related Patents

  1. Kowalski A, Björnsson E, Mueller T C. "一种(1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环)的合成方法" [P]. European Patent, EP 3214046 A1, 2017-12-05.
  2. 发明人罗永刚，朱建伟，徐明华. "Method for the Synthesis of (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy)]bis[(6-methoxy-4-quinolyl)methylene]]bis(3-ethylquinuclidine)" [P]. 中国发明专利, 专利号 CN 116730151 A, 授权公告日 2016-08-01.
  3. Johansson L, Rossi M, Björnsson E. "A Process for Preparing High-Purity (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-Diphenylpyrimidine-4,6-diyl)bis(oxy)]bis[(6-methoxy-4-quinolyl)methylene]]bis(3-ethylquinuclidine)" [P]. European Patent, EP 3000971 A1, 2025-04-05.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环) in Pharmaceutical Formulations". Food Chem., 2013, 1461, 4357-4369.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of (1S,1’S,3R,3’R,4S,4’S,6S,6’S)-6,6’-[(1R,1’R)-[(2,5-二苯基嘧啶-4,6-二基)双(氧基)]双[(6-甲氧基-4-喹啉基)亚甲基]]双(3-乙基奎宁环) as an Impurity". Environ. Sci. Technol., 2021, 1008, (8), 9880-9895.

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