CAS 15272-95-4

FZ46ONU496 15272-95-4 Macrogol 4000 [INN] Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 108963 UNII-FZ46ONU496

纯度 97%+现货药物标准品
CAS 号15272-95-4
分子式C15H21N2OS Cl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

FZ46ONU496 15272-95-4 Macrogol 4000 [INN] Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 108963 UNII-FZ46ONU496 CAS 15272-95-4 结构式 Chemical Structure

产品介绍 Description

（英文名 FZ46ONU496 15272-95-4 Macrogol 4000 [INN] Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 108963 UNII-FZ46ONU496，CAS 15272-95-4）属于药物标准品。分子式 C15H21N2OS Cl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括在内的目标物的控制。 化学式为 C15H21N2OS Cl 的（FZ46ONU496 15272-95-4 Macrogol 4000 INN Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 108963 UNII-FZ46ONU496），其CAS登记号是 15272-95-4，分子量为 312.86 g/mol。 （分子式 C15H21N2OS Cl）的化学结构中包含含氮杂环结构，酰胺类，含硫有机，含羟基，含醚键，含氯取代。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响

应用场景：针对化学分析用途，（FZ46ONU496 15272-95-4 Macrogol 4000 INN Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 10896

理化性质 Physical & Chemical Properties

中文名称
分子式C15H21N2OS Cl
分子量312.86 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1961年
卤素含量Cl取代
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. 发明人郑宇鹏，周伟，王建平. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 117424161 A, 授权公告日 2021-03-04.
  2. 发明人李文辉，马晓峰，王建平. "Method for the Synthesis of FZ46ONU496 15272-95-4 Macrogol 4000 [INN] Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 108963 UNII-FZ46ONU496" [P]. 中国发明专利, 专利号 CN 109792560 A, 授权公告日 2024-07-14.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Chromatographia, 2023, 2251, (8), 2809-2829.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Chemosphere, 2015, 2471, (10), 7459-7474.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of FZ46ONU496 15272-95-4 Macrogol 4000 [INN] Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, hydrochloride Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride N-(2-(Diethylamino)ethyl)benzo(b)thiophene-2-carboxamide hydrochloride Macrogol 4000 NSC 108963 UNII-FZ46ONU496 Using HRMS and NMR". Sci. Total Environ., 2010, 1387, 8809-8822.
  4. Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". Food Chem., 2025, 1731, (8), 6666-6686.

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