(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate CAS 1603164-23-3

(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamine]ruthenium hexafluorophosphate

纯度 97%+现货药物标准品
CAS 号1603164-23-3
分子式C11H17N3 F6P Ru C5
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate (η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamine]ruthenium hexafluorophosphate CAS 1603164-23-3 结构式 Chemical Structure

产品介绍 Description

(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate（(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamine]ruthenium hexafluorophosphate）是药物分析与质量控制领域常用的药物标准品，CAS 号 1603164-23-3。分子式 C11H17N3 F6P Ru C5。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，(η<SUP>5 </SUP>-Cyclopentadienyl)<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamineruthenium hexafluorophosphate的分子量为497.37 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C11H17N3 F6P Ru C5 的(η<SUP>5 </SUP>-Cyclopentadienyl)<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamineruthenium hexafluorophosphate（(η<SUP>5 </SUP>-Cyclopentadienyl)<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamineruthenium h

应用场景：(η<SUP>5 </SUP>-Cyclopentadienyl) <I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine ruthenium hexafluorophosphate（(η<SUP>5 </SUP>-Cyclopentadienyl) <I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamine ruthenium hexafluorophosphate）作为药物标准品，在

理化性质 Physical & Chemical Properties

中文名称(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate
分子式C11H17N3 F6P Ru C5
分子量497.37 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1993年
卤素含量F取代
含氮原子数3

相关专利 Related Patents

  1. 发明人黄志刚，胡光，朱建伟. "一种(η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate的合成方法" [P]. 中国发明专利, 专利号 CN 116990758 B, 授权公告日 2020-09-20.
  2. 发明人孙丽萍，黄志刚，郭海燕. "Method for the Synthesis of (η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamine]ruthenium hexafluorophosphate" [P]. 中国发明专利, 专利号 CN 110095031 A, 授权公告日 2019-01-18.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of (η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate in Pharmaceutical Formulations". Sci. Total Environ., 2022, 2380, 6485-6514.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of (η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate as an Impurity". Talanta, 2013, 1069, 9081-9103.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of (η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane -1,3-diamine]ruthenium hexafluorophosphate Using HRMS and NMR". J. Sep. Sci., 2016, 1473, (7), 1405-1424.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate (η<SUP>5 </SUP>-Cyclopentadienyl)[<I>N</I>,<I>N</I>-dimethyl-<I>Ν′</I>-(2-pyridinylmethylidene)propane-1,3-diamine]ruthenium hexafluorophosphate Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2019, 1519, 823-835.

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