3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride CAS 1786215-62-0

3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride

纯度 97%+现货药物标准品
CAS 号1786215-62-0
分子式C11H15N3O 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride CAS 1786215-62-0 结构式 Chemical Structure

产品介绍 Description

3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride（3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 1786215-62-0。分子式 C11H15N3O 2*HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride的分子量为241.72 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 1786215-62-0 对应的化合物3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride（英文标识 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride），化学式 C11H15N3O 2HCl，相对分子质量 241.72。 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride（C11H15N3O 2HCl）含有含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代。卤素取代增加了化合物的密度和沸点，较高的碳

应用场景：3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride（3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙

理化性质 Physical & Chemical Properties

中文名称3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride
分子式C11H15N3O 2*HCl
分子量241.72 g/mol
外观形态类白色至淡黄色低熔点固体。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1994年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人韩伟，孙丽萍，张德明. "一种3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 113536004 B, 授权公告日 2015-03-08.
  2. Thompson G K, Park J H, Fischer A B. "Method for the Synthesis of 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride" [P]. US Patent, US 11648249 B2, 2015-07-23.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride in Pharmaceutical Formulations". Food Chem., 2020, 297, (8), 7139-7144.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride as an Impurity". Anal. Chim. Acta, 2012, 1400, (12), 8358-8375.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride Using HRMS and NMR". Environ. Sci. Technol., 2024, 1506, (6), 6378-6402.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 3-amino-6-(dimethylamino)-1-methyl-2,3-dihydro-1H-indol-2-one dihydrochloride Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2023, 1630, (4), 3457-3482.

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