lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate CAS 1803561-87-6

lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate

纯度 97%+现货药物标准品
CAS 号1803561-87-6
分子式C12H22NO5 Li
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate CAS 1803561-87-6 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate（lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate，CAS 1803561-87-6），分子式 C12H22NO5 Li。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

lithium(1+) ion 2-{(tert-butoxy)carbonyl(methyl)amino}-4-hydroxy-4-methylpentanoate的产生途径与其化学式中氨基酸衍生物，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 1803561-87-6 对应的化合物lithium(1+) ion 2-{(tert-butoxy)carbonyl(methyl)amino}-4-hydroxy-4-methylpentanoate（英文标识 lithium(1+) ion 2-{(tert-butoxy)carbonyl(methyl)amino}-4-hydroxy-4-methylpentanoate），化学式 C12H22NO5 Li，相对分子质量 267.25。 lithium(1+) ion 2-{(tert-butoxy)carbonyl(methyl)amino}-4-hydroxy-4-methylpentanoate（分子式 C12H22NO5 Li）的化学结构中包含氨基

应用场景：针对化学分析用途，lithium(1+) ion 2-{ (tert-butoxy)carbonyl (methyl)amino}-4-hydroxy-4-methylpentanoate（lithium(1+) ion 2-{ (tert-butoxy)carbonyl (methyl)amino}-4-hydroxy-4-methylpentanoate）是具有明确定量溯源的认证级对照品。 推荐以lithium(1+) ion 2-{ (tert-butoxy)carbonyl (methyl)amino}-4-hydroxy-4-methylpentanoate配制标准系列工作溶液，用

理化性质 Physical & Chemical Properties

中文名称lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate
分子式C12H22NO5 Li
分子量267.25 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）1995年
含氮原子数1

相关专利 Related Patents

  1. Park J H, Schröder R, Stevens L M. "一种lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate的合成方法" [P]. US Patent, US 9277555 B2, 2018-12-21.
  2. 发明人郭海燕，胡光，徐明华. "Method for the Synthesis of lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate" [P]. 中国发明专利, 专利号 CN 113014996 A, 授权公告日 2022-10-24.
  3. 发明人陈志强，何建平，郑宇鹏. "A Process for Preparing High-Purity lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate" [P]. 中国发明专利, 专利号 CN 111711994 B, 授权公告日 2020-12-06.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate in Pharmaceutical Formulations". Talanta, 2010, 1781, (5), 3558-3570.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate as an Impurity". Chemosphere, 2014, 1204, (10), 275-305.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate Using HRMS and NMR". J. Nat. Prod., 2010, 217, (7), 3473-3501.

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