[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride CAS 1803566-58-6

[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1803566-58-6
分子式C9H16N4O 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride CAS 1803566-58-6 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride（[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride）为药物标准品，CAS 登记号 1803566-58-6，分子式 C9H16N4O 2*HCl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-ylmethanamine dihydrochloride的分子量为232.71 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-ylmethanamine dihydrochloride（1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-ylmethanamine dihydrochloride），CAS注册编号 1803566-58-6，化学分子式为 C9H16N4O 2HCl，分子量 232.71 g/mol。 1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-ylmethanamine dihydrochloride（C9H16N4O 2HCl）含有酰胺类，含羟基，含醚键，含氯取代。卤素取代增加了化合物的密度和沸点，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。因

应用场景： 1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl methanamine dihydrochloride（ 1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl methanamine dihydrochloride，CAS 1803566-58-6）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以 1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl methanamine dihydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲

理化性质 Physical & Chemical Properties

中文名称[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride
分子式C9H16N4O 2*HCl
分子量232.71 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. 发明人冯建国，朱建伟，唐晓军. "一种[1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 113140917 B, 授权公告日 2016-12-22.
  2. 发明人林芳，韩伟，王建平. "Method for the Synthesis of [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride" [P]. 中国发明专利, 专利号 CN 116613919 A, 授权公告日 2017-11-13.
  3. 发明人沈红梅，高志强，杨光. "A Process for Preparing High-Purity [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride" [P]. 中国发明专利, 专利号 CN 117686893 B, 授权公告日 2021-01-24.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride in Pharmaceutical Formulations". J. Chromatogr. A, 2015, 1527, (3), 827-844.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride as an Impurity". Environ. Sci. Technol., 2013, 2437, (4), 7165-7179.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride Using HRMS and NMR". Sci. Total Environ., 2010, 1548, (7), 3157-3167.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate [1-(1,2,4-oxadiazol-3-ylmethyl)piperidin-3-yl]methanamine dihydrochloride Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2024, 872, 6223-6246.

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