dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride CAS 1803588-70-6

dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1803588-70-6
分子式C11H24N2 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride CAS 1803588-70-6 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride（dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride）为药物标准品，CAS 登记号 1803588-70-6，分子式 C11H24N2 2*HCl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括dimethyl2-methyl-2-(piperidin-4-yl)propylamine dihydrochloride在内的目标物的控制。 dimethyl2-methyl-2-(piperidin-4-yl)propylamine dihydrochloride（dimethyl2-methyl-2-(piperidin-4-yl)propylamine dihydrochloride），CAS注册编号 1803588-70-6，化学分子式为 C11H24N2 2HCl，分子量 220.78 g/mol。 从化学结构特征来看，dimethyl2-methyl-2-(piperidin-4-yl)propylamine dihydrochloride的分子骨架中包含含氯取代。该化合物的不饱和度为0.0，表明结构中存在约0个环或双键等价单元。分子量为220.78 g/mol，属于中等分子量化合物。因分子内存在卤素取代基（F/Cl/Br/I），该化合物在质谱分析中呈现特征性的同位素分布模式，可作为定性确

应用场景：从实际应用出发，dimethyl 2-methyl-2-(piperidin-4-yl)propyl amine dihydrochloride（CAS 1803588-70-6）在化学分析中作为关键的基准对照物质。 推荐以dimethyl 2-methyl-2-(piperidin-4-yl)propyl amine dihydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于2-8°C冷藏保存，避

理化性质 Physical & Chemical Properties

中文名称dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride
分子式C11H24N2 2*HCl
分子量220.78 g/mol
外观形态白色至类白色低熔点固体。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. Rossi M, Lefèvre J P, Sørensen M. "一种dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride的合成方法" [P]. European Patent, EP 3826875 A1, 2023-07-13.
  2. Martínez F, Björnsson E, Rossi M. "Method for the Synthesis of dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride" [P]. European Patent, EP 3817507 A1, 2025-10-23.
  3. 发明人钱学锋，高志强，孙丽萍. "A Process for Preparing High-Purity dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride" [P]. 中国发明专利, 专利号 CN 114144100 A, 授权公告日 2018-02-02.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2024, 2172, (11), 6864-6889.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride as an Impurity". Chemosphere, 2025, 874, 9352-9380.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride Using HRMS and NMR". J. Pharm. Biomed. Anal., 2013, 977, 4540-4567.
  4. Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate dimethyl[2-methyl-2-(piperidin-4-yl)propyl]amine dihydrochloride Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2022, 2371, (3), 5906-5932.

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