[3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride CAS 1803592-07-5

[3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride

纯度 97%+现货药物标准品
CAS 号1803592-07-5
分子式C14H23N5O 3*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

[3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride [3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride CAS 1803592-07-5 结构式 Chemical Structure

产品介绍 Description

[3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride（英文名 [3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride，CAS 1803592-07-5）属于药物标准品。分子式 C14H23N5O 3*HCl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo1,5-apyridin-5-ylmethanamine trihydrochloride在内的目标物的控制。 化学式为 C14H23N5O 3HCl 的3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo1,5-apyridin-5-ylmethanamine trihydrochloride（3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo1,5-apyridin-5-ylmethanamine trihydrochloride），其CAS登记号是 1803592-07-5，分子量为 313.83 g/mol。 3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo1,5-apyridin-5-ylmethana

应用场景： 3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo 1,5-a pyridin-5-yl methanamine trihydrochloride（ 3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo 1,5-a pyridin-5-yl methanamine trihydrochloride）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以 3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo 1,5-a

理化性质 Physical & Chemical Properties

中文名称[3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride
分子式C14H23N5O 3*HCl
分子量313.83 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数5

相关专利 Related Patents

  1. Nowak P, Jørgensen K, Lefèvre J P. "一种[3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride的合成方法" [P]. European Patent, EP 3263374 A1, 2015-09-01.
  2. Davis P L, Mueller T, Chen K W. "Method for the Synthesis of [3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride" [P]. US Patent, US 11029999 B2, 2018-05-05.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of [3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride in Pharmaceutical Formulations". J. Sep. Sci., 2025, 442, (9), 5900-5919.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of [3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride as an Impurity". J. Chromatogr. A, 2018, 927, (7), 279-307.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of [3-(4-methylpiperazine-1-carbonyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-yl]methanamine trihydrochloride Using HRMS and NMR". Molecules, 2014, 914, 754-760.

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