5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride CAS 1803592-76-8

5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride

纯度 97%+现货药物标准品
CAS 号1803592-76-8
分子式C7H10N6O HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride 5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride CAS 1803592-76-8 结构式 Chemical Structure

产品介绍 Description

5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride（5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 1803592-76-8。分子式 C7H10N6O HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在质量保证方面，5-methyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)methyl-1H-1,2,3-triazol-4-amine hydrochloride的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 5-methyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)methyl-1H-1,2,3-triazol-4-amine hydrochloride（5-methyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)methyl-1H-1,2,3-triazol-4-amine hydrochloride），CAS注册编号 1803592-76-8，化学分子式为 C7H10N6O HCl，分子量 230.66 g/mol。 5-methyl-1-(5-methyl-1,2,

应用场景：从实际应用出发，5-methyl-1- (5-methyl-1,2,4-oxadiazol-3-yl)methyl -1H-1,2,3-triazol-4-amine hydrochloride（CAS 1803592-76-8）在化学分析中作为关键的基准对照物质。 推荐以5-methyl-1- (5-methyl-1,2,4-oxadiazol-3-yl)methyl -1H-1,2,3-triazol-4-amine hydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建

理化性质 Physical & Chemical Properties

中文名称5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride
分子式C7H10N6O HCl
分子量230.66 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数6

相关专利 Related Patents

  1. 发明人钱学锋，徐明华，孙丽萍. "一种5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 113962170 A, 授权公告日 2021-07-17.
  2. 发明人郭海燕，赵玉洁，罗永刚. "Method for the Synthesis of 5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride" [P]. 中国发明专利, 专利号 CN 111013353 A, 授权公告日 2024-10-05.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride in Pharmaceutical Formulations". Food Chem., 2021, 1559, (3), 8717-8728.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride as an Impurity". Biomed. Chromatogr., 2011, 1668, (12), 2375-2389.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride Using HRMS and NMR". J. Pharm. Biomed. Anal., 2019, 1451, (3), 2755-2764.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 5-methyl-1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-1H-1,2,3-triazol-4-amine hydrochloride Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2023, 839, (6), 830-851.

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