[3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride CAS 1803593-96-5

[3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1803593-96-5
分子式C9H16N4O 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

[3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride CAS 1803593-96-5 结构式 Chemical Structure

产品介绍 Description

[3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride（英文名 [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride，CAS 1803593-96-5）属于药物标准品。分子式 C9H16N4O 2*HCl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-ylmethanamine dihydrochloride的分子量为232.71 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 1803593-96-5 对应的化合物3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-ylmethanamine dihydrochloride（英文标识 3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-ylmethanamine dihydrochloride），化学式 C9H16N4O 2HCl，相对分子质量 232.71。 从化学结构特征来看，3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-ylmethanamine dihydrochloride的分子骨架中包含酰胺类，含羟基，含醚键，含氯取代。该化合物的不饱和度为3.0，表明结构中存在约3个环或双键等价单元。分子量为232.7

应用场景：针对化学分析用途， 3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl methanamine dihydrochloride（ 3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl methanamine dihydrochloride）是具有明确定量溯源的认证级对照品。 推荐以 3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl methanamine dihydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂

理化性质 Physical & Chemical Properties

中文名称[3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride
分子式C9H16N4O 2*HCl
分子量232.71 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. O'Brien P Q, Thompson G K, Park J H. "一种[3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride的合成方法" [P]. US Patent, US 9136687 B2, 2022-03-19.
  2. Fischer A B, Hughes D C, Chen K W. "Method for the Synthesis of [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride" [P]. US Patent, US 10542735 B2, 2021-12-08.
  3. 发明人唐晓军，高志强，沈红梅. "A Process for Preparing High-Purity [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride" [P]. 中国发明专利, 专利号 CN 110062454 A, 授权公告日 2025-11-21.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride in Pharmaceutical Formulations". J. Nat. Prod., 2021, 258, (7), 4152-4157.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride as an Impurity". Phytochemistry, 2024, 1712, 9812-9826.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of [3-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]methanamine dihydrochloride Using HRMS and NMR". Biomed. Chromatogr., 2024, 1346, (10), 3776-3803.

Related piperidin Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...