11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione CAS 1809737-28-7

11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione

纯度 97%+现货药物标准品
CAS 号1809737-28-7
分子式C17H16N2O3
分子量296.32 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione CAS 1809737-28-7 结构式 Chemical Structure

产品介绍 Description

11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione（英文名 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione，CAS 1809737-28-7）属于药物标准品。分子式 C17H16N2O3，分子量 296.32。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，11-Ethyl-6,8-Dimethyloxazolo5,4,3-IjPyrido3,2-GQuinoline-4,10(2H,11H)-Dione的分子量为296.32 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 11-Ethyl-6,8-Dimethyloxazolo5,4,3-IjPyrido3,2-GQuinoline-4,10(2H,11H)-Dione（11-Ethyl-6,8-Dimethyloxazolo5,4,3-IjPyrido3,2-GQuinoline-4,10(2H,11H)-Dione），CAS注册编号 1809737-28-7，化学分子式为 C17H16N2O3，分子量 296.32 g/mol。 受分子结构中甾体骨架，酰胺类，含羟基，含醚键的影响，11-Ethyl-6,8-Dimethyloxazolo5,4,3-IjPyrido3,2-GQuinoline-4,10(2H,11H)-Dione表现为淡黄色至黄色结晶性粉末。其固体形态的物理化学属性——包括296.32

应用场景：11-Ethyl-6,8-Dimethyloxazolo 5,4,3-Ij Pyrido 3,2-G Quinoline-4,10(2H,11H)-Dione（11-Ethyl-6,8-Dimethyloxazolo 5,4,3-Ij Pyrido 3,2-G Quinoline-4,10(2H,11H)-Dione）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以11-Ethyl-6,8-Dimethyloxazolo 5,4,3-Ij Pyrido 3,2-G Quinoline-4,10(2H,11H)-Dione配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议

理化性质 Physical & Chemical Properties

中文名称11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione
分子式C17H16N2O3
分子量296.32 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
含氮原子数2

相关专利 Related Patents

  1. 发明人钱学锋，陈志强，朱建伟. "一种11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione的合成方法" [P]. 中国发明专利, 专利号 CN 112372985 A, 授权公告日 2020-09-19.
  2. Park J H, Klinger H, Thompson G K. "Method for the Synthesis of 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione" [P]. US Patent, US 10084067 B2, 2018-11-05.
  3. Roberts E F, Klinger H, Schröder R. "A Process for Preparing High-Purity 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione" [P]. US Patent, US 10386747 B2, 2018-04-14.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione in Pharmaceutical Formulations". Anal. Methods, 2021, 1326, (9), 7062-7081.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione as an Impurity". Talanta, 2018, 2094, 3600-3614.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione Using HRMS and NMR". J. Pharm. Biomed. Anal., 2022, 1831, 7968-7972.
  4. Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate 11-Ethyl-6,8-Dimethyloxazolo[5,4,3-Ij]Pyrido[3,2-G]Quinoline-4,10(2H,11H)-Dione Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2022, 1168, (7), 9127-9145.

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