CAS 183305-24-0

10NHF3008V 183305-24-0 Fidexaban [USAN:INN] Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy)pyridin-4-yl)methylamino)acetic acid ZK 807834 UNII-10NHF3008V

纯度 97%+现货药物标准品
CAS 号183305-24-0
分子式C25H24F2N6O5
分子量526.49 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

10NHF3008V 183305-24-0 Fidexaban [USAN:INN] Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy)pyridin-4-yl)methylamino)acetic acid ZK 807834 UNII-10NHF3008V CAS 183305-24-0 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的（10NHF3008V 183305-24-0 Fidexaban [USAN:INN] Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy)pyridin-4-yl)methylamino)acetic acid ZK 807834 UNII-10NHF3008V）为药物标准品，CAS 登记号 183305-24-0，分子式 C25H24F2N6O5，分子量 526.49。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，的分子量为526.49 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C25H24F2N6O5 的（10NHF3008V 183305-24-0 Fidexaban USAN:INN Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy)pyridin-4-yl)methylamino)acetic acid ZK 807834 UNII-10NHF3008V），其CAS登记号是 183305-24-0，分子量为 526.49 g/mol。 依据分子式为 C25H24F2

应用场景：针对化学分析用途，（10NHF3008V 183305-24-0 Fidexaban USAN:INN Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-

理化性质 Physical & Chemical Properties

中文名称
分子式C25H24F2N6O5
分子量526.49 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）16.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2009年
卤素含量F取代
含氮原子数6

相关专利 Related Patents

  1. 发明人赵玉洁，孙丽萍，林芳. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 115147064 A, 授权公告日 2020-09-18.
  2. Schröder R, Lefèvre J P, Björnsson E. "Method for the Synthesis of 10NHF3008V 183305-24-0 Fidexaban [USAN:INN] Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy)pyridin-4-yl)methylamino)acetic acid ZK 807834 UNII-10NHF3008V" [P]. European Patent, EP 3256179 A1, 2020-01-26.
  3. 发明人钱学锋，马晓峰，郭海燕. "A Process for Preparing High-Purity 10NHF3008V 183305-24-0 Fidexaban [USAN:INN] Glycine, N-(2-(5-(aminoiminomethyl)-2-hydroxyphenoxy)-6-(3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy)-3,5-difluoro-4-pyridinyl)-N-methyl- Fidexaban ((2-(5-Carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-(3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy)pyridin-4-yl)methylamino)acetic acid ZK 807834 UNII-10NHF3008V" [P]. 中国发明专利, 专利号 CN 114304607 A, 授权公告日 2022-04-20.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Environ. Sci. Technol., 2018, 1983, 293-306.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Sci. Total Environ., 2023, 851, (10), 7657-7672.

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