(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride CAS 1929582-61-5

(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride

纯度 97%+现货药物标准品
CAS 号1929582-61-5
分子式C11H13NO3 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride (1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride CAS 1929582-61-5 结构式 Chemical Structure

产品介绍 Description

(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride（(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 1929582-61-5。分子式 C11H13NO3 HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride的分子量为243.69 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C11H13NO3 HCl 的(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride（(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride），其CAS登记号是 1929582-61-5，分子量为 243.69 g/mol。 从化学结构特征来看，(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride的分子骨架中包含含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代。该化合物的不饱和度为5.0，表明结构中存在约5个环或

应用场景：(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride（(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride，CAS 1929582-61-5）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride配制标准系列工作溶液，用于建立标准曲线实现

理化性质 Physical & Chemical Properties

中文名称(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride
分子式C11H13NO3 HCl
分子量243.69 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1996年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. Anderson J P, Mueller T, Stevens L M. "一种(1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride的合成方法" [P]. US Patent, US 11354307 B2, 2022-05-08.
  2. Johnson M A, Brown S R, Chen K W. "Method for the Synthesis of (1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride" [P]. US Patent, US 10854807 B2, 2015-04-04.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of (1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride in Pharmaceutical Formulations". Chromatographia, 2020, 164, (12), 7773-7776.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of (1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride as an Impurity". Anal. Methods, 2016, 1323, (7), 208-233.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of (1S)-5-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride Using HRMS and NMR". Anal. Chem., 2018, 1172, (6), 4784-4814.

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