氯化四苯磷 CAS 2001-45-8

2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride

纯度 97%+现货药物标准品
CAS 号2001-45-8
分子式C24H44P Cl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

氯化四苯磷 2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride CAS 2001-45-8 结构式 Chemical Structure

产品介绍 Description

氯化四苯磷（英文名 2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride，CAS 2001-45-8）属于药物标准品。分子式 C24H44P Cl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，氯化四苯磷的分子量为399.04 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 氯化四苯磷（2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride），CAS注册编号 2001-45-8，化学分子式为 C24H44P Cl，分子量 399.04 g/mol。 氯化四苯磷（C24H44P Cl）含有有机磷，含氯取代。卤素取代增加了化合物的密度和沸点，较高的碳氢比使其脂溶性较好，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。

应用场景：氯化四苯磷（2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride，CAS 2001-4

理化性质 Physical & Chemical Properties

中文名称氯化四苯磷
分子式C24H44P Cl
分子量399.04 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）1957年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人杨光，刘建华，罗永刚. "一种氯化四苯磷的合成方法" [P]. 中国发明专利, 专利号 CN 110624814 B, 授权公告日 2018-10-11.
  2. 发明人韩伟，张德明，高志强. "Method for the Synthesis of 2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride" [P]. 中国发明专利, 专利号 CN 115757806 B, 授权公告日 2022-07-10.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 氯化四苯磷 in Pharmaceutical Formulations". J. Agric. Food Chem., 2023, 1305, 4544-4555.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 氯化四苯磷 as an Impurity". Talanta, 2019, 1166, 7946-7956.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride Using HRMS and NMR". Anal. Chim. Acta, 2020, 528, (9), 1610-1634.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 氯化四苯磷 Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2024, 1220, 3153-3159.

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