rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid CAS 2031242-15-4

rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid

纯度 97%+现货药物标准品
CAS 号2031242-15-4
分子式C11H15N3O3
分子量237.26 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid CAS 2031242-15-4 结构式 Chemical Structure

产品介绍 Description

rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid（英文名 rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid，CAS 2031242-15-4）属于药物标准品。分子式 C11H15N3O3，分子量 237.26。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid在内的目标物的控制。 rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid（rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid），CAS注册编号 2031242-15-4，化学分子式为 C11H15N3O3，分子量 237.26 g/mol。 受分子结构中氨基酸衍生物，酰胺类，含羟基，含醚键的影响，rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid表现为类白色至淡黄色结晶性粉末。其

应用场景：rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid（rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid配制标

理化性质 Physical & Chemical Properties

中文名称rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid
分子式C11H15N3O3
分子量237.26 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1996年
含氮原子数3

相关专利 Related Patents

  1. 发明人沈红梅，王建平，郑宇鹏. "一种rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid的合成方法" [P]. 中国发明专利, 专利号 CN 114043256 A, 授权公告日 2025-01-27.
  2. 发明人韩伟，黄志刚，钱学锋. "Method for the Synthesis of rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid" [P]. 中国发明专利, 专利号 CN 113230039 A, 授权公告日 2017-01-26.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid in Pharmaceutical Formulations". J. Nat. Prod., 2023, 1240, 4556-4584.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid as an Impurity". Rapid Commun. Mass Spectrom., 2017, 2329, (4), 8347-8357.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid Using HRMS and NMR". Anal. Chem., 2011, 406, 5790-5815.
  4. Wang L, Li J, Zhang H. "Forced Degradation Studies to Evaluate rac-(2R,3R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2013, 908, 80-110.

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