Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH CAS 205528-30-9

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-ylpropanoic acid (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-pyridin-4-ylpropanoic acid 205528-30-9 Fmoc-D-4-Pyridylalanine

纯度 97%+现货药物标准品
CAS 号205528-30-9
分子式C23H38N2O4
分子量406.56 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-ylpropanoic acid (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-pyridin-4-ylpropanoic acid 205528-30-9 Fmoc-D-4-Pyridylalanine CAS 205528-30-9 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH（(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-ylpropanoic acid (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-pyridin-4-ylpropanoic acid 205528-30-9 Fmoc-D-4-Pyridylalanine）为药物标准品，CAS 登记号 205528-30-9，分子式 C23H38N2O4，分子量 406.56。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH在内的目标物的控制。 化学式为 C23H38N2O4 的Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH（(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-ylpropanoic acid (2R)-2-9H-fluoren-9-ylmethoxy(oxo)methylamino-3-pyridin-4-ylpropanoic a

应用场景：Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH（(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino

理化性质 Physical & Chemical Properties

中文名称Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH
分子式C23H38N2O4
分子量406.56 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2015年
含氮原子数2

相关专利 Related Patents

  1. 发明人周伟，郑宇鹏，唐晓军. "一种Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH的合成方法" [P]. 中国发明专利, 专利号 CN 116165339 A, 授权公告日 2017-05-21.
  2. 发明人李文辉，林芳，陈志强. "Method for the Synthesis of (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-ylpropanoic acid (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-pyridin-4-ylpropanoic acid 205528-30-9 Fmoc-D-4-Pyridylalanine" [P]. 中国发明专利, 专利号 CN 108193577 A, 授权公告日 2022-04-26.
  3. Yamamoto T, Chen K W, Thompson G K. "A Process for Preparing High-Purity (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-pyridyl)propionic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-yl-propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-pyridin-4-ylpropanoic acid (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-pyridin-4-ylpropanoic acid 205528-30-9 Fmoc-D-4-Pyridylalanine" [P]. US Patent, US 11766308 B2, 2022-08-28.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2022, 455, (5), 8994-9008.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of Fmoc-β——（4-吡啶基）-<SC> D </SC>-Ala-OH as an Impurity". Chemosphere, 2023, 2447, 8164-8192.

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