3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride CAS 2060024-59-9

3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride

纯度 97%+现货药物标准品
CAS 号2060024-59-9
分子式C12H11F3N4O 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride 3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride CAS 2060024-59-9 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride（3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride）为药物标准品，CAS 登记号 2060024-59-9，分子式 C12H11F3N4O 2*HCl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，3-{5-3-(trifluoromethyl)pyrrolidin-3-yl-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride的分子量为320.70 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C12H11F3N4O 2HCl 的3-{5-3-(trifluoromethyl)pyrrolidin-3-yl-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride（3-{5-3-(trifluoromethyl)pyrrolidin-3-yl-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride），其CAS登记号是 2060024-59-9，分子量为 320.70 g/mol。 依据分子式为 C12H11F3N4O 2HCl 的3-{5-3-(trifluoromethyl)pyrrolidin-3-yl-1,2,4-oxadiazol-3-yl}pyridine dihydrochlori

应用场景：针对化学分析用途，3-{5- 3-(trifluoromethyl)pyrrolidin-3-yl -1,2,4-oxadiazol-3-yl}pyridine dihydrochloride（3-{5- 3-(trifluoromethyl)pyrrolidin-3-yl -1,2,4-oxadiazol-3-yl}pyridine dihydrochloride）是具有明确定量溯源的认证级对照品。 推荐以3-{5- 3-(trifluoromethyl)pyrrolidin-3-yl -1,2,4-oxadiazol-3-yl}pyridine dihydrochloride配制标准系列

理化性质 Physical & Chemical Properties

中文名称3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride
分子式C12H11F3N4O 2*HCl
分子量320.70 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1997年
卤素含量F/Cl取代
含氮原子数4

相关专利 Related Patents

  1. 发明人郭海燕，周伟，冯建国. "一种3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 108729278 A, 授权公告日 2024-05-13.
  2. 发明人沈红梅，罗永刚，杨光. "Method for the Synthesis of 3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride" [P]. 中国发明专利, 专利号 CN 117033454 B, 授权公告日 2021-06-28.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride in Pharmaceutical Formulations". J. Chromatogr. A, 2019, 1523, (1), 8397-8409.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride as an Impurity". Sci. Total Environ., 2013, 912, 8155-8181.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of 3-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride Using HRMS and NMR". Talanta, 2021, 2438, (11), 2268-2278.

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