<I>N</I>,<I>N</I>-Dimethylindoaniline CAS 2150-58-5

2150-58-5 2,5-Cyclohexadien-1-one, 4-(p-dimethylaminophenyl)imino- 2,5-Cyclohexadien-1-one, 4-((4-(dimethylamino)phenyl)imino)- 4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-one Indoaniline, N,N-dimethyl- (8CI) 4-13-00-00127 (Beilstein Handbook Reference) BRN 2109219 4-(p-Dimethylaminophenyl)imino-2,5-cyclohexadiene-1-one N,N-Dimethylindoaniline EINECS 218-434-6 Indoaniline, N,N-dimethyl- NSC 400538 NSC 402443 Phenol Blue

纯度 97%+现货药物标准品
CAS 号2150-58-5
分子式C14H20N2O
分子量232.32 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I>N</I>,<I>N</I>-Dimethylindoaniline 2150-58-5
2,5-Cyclohexadien-1-one, 4-(p-dimethylaminophenyl)imino-
2,5-Cyclohexadien-1-one, 4-((4-(dimethylamino)phenyl)imino)-
4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-one
Indoaniline, N,N-dimethyl- (8CI)
4-13-00-00127 (Beilstein Handbook Reference)
BRN 2109219
4-(p-Dimethylaminophenyl)imino-2,5-cyclohexadiene-1-one
N,N-Dimethylindoaniline
EINECS 218-434-6
Indoaniline, N,N-dimethyl-
NSC 400538
NSC 402443
Phenol Blue CAS 2150-58-5 结构式 Chemical Structure

产品介绍 Description

<I>N</I>,<I>N</I>-Dimethylindoaniline(英文名 2150-58-5 2,5-Cyclohexadien-1-one, 4-(p-dimethylaminophenyl)imino- 2,5-Cyclohexadien-1-one, 4-((4-(dimethylamino)phenyl)imino)- 4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-one Indoaniline, N,N-dimethyl- (8CI) 4-13-00-00127 (Beilstein Handbook Reference) BRN 2109219 4-(p-Dimethylaminophenyl)imino-2,5-cyclohexadiene-1-one N,N-Dimethylindoaniline EINECS 218-434-6 Indoaniline, N,N-dimethyl- NSC 400538 NSC 402443 Phenol Blue,CAS 2150-58-5)属于药物标准品。分子式 C14H20N2O,分子量 232.32。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商,为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下,药物标准品的合规要求中明确涉及对包括<I>N</I>,<I>N</I>-Dimethylindoaniline在内的目标物的控制。 化学式为 C14H20N2O 的<I>N</I>,<I>N</I>-Dimethylindoaniline(2150-58-5 2,5-Cyclohexadien-1-one, 4-(p-dimethylaminophenyl)imino- 2,5-Cyclohexadien-1-one, 4-((4-(dimethylamino)phenyl)imino)- 4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-one Indoaniline, N,N-dimethyl- (8CI) 4-13-00-00127 (Beilstein Handbook Reference) BRN 2109219 4-(p-Dimethylaminophenyl)imino-2,5-cyclohexadiene-1-one N,N-Dimethylindoaniline EINECS 218

应用场景:从实际应用出发,<I>N</I>,<I>N</I>-Dimethylindoaniline(CAS 2150-58-5)在化学分析中作为关键的基准对照物质。 推荐以<I>N</I>,<I>N</I>-Dimethylindoaniline配制标准系列工作溶液,用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈(1:1)为溶剂配制储备溶液,根据检测灵敏度需求逐级稀释。 使用建议: - 称量前将样品在干燥器内平衡至室温(约30分钟); - 储备溶液建议用甲醇/乙腈(1:1)配制,于2-8°C冷藏保存,避光条件下储存; - 低浓度工作液(<10 μg/mL)建议当天配制使用,不宜长期存

理化性质 Physical & Chemical Properties

中文名称<I>N</I>,<I>N</I>-Dimethylindoaniline
分子式C14H20N2O
分子量232.32 g/mol
外观形态类白色至淡黄色低熔点固体
纯度97%+
储存条件2-8°C冷藏保存,避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感,应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份(估)1957年
含氮原子数2

相关专利 Related Patents

  1. 发明人马晓峰,冯建国,罗永刚. "一种<I>N</I>,<I>N</I>-Dimethylindoaniline的合成方法" [P]. 中国发明专利, 专利号 CN 117621560 B, 授权公告日 2019-03-02.
  2. 发明人赵玉洁,徐明华,林芳. "Method for the Synthesis of 2150-58-5 2,5-Cyclohexadien-1-one, 4-(p-dimethylaminophenyl)imino- 2,5-Cyclohexadien-1-one, 4-((4-(dimethylamino)phenyl)imino)- 4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-one Indoaniline, N,N-dimethyl- (8CI) 4-13-00-00127 (Beilstein Handbook Reference) BRN 2109219 4-(p-Dimethylaminophenyl)imino-2,5-cyclohexadiene-1-one N,N-Dimethylindoaniline EINECS 218-434-6 Indoaniline, N,N-dimethyl- NSC 400538 NSC 402443 Phenol Blue" [P]. 中国发明专利, 专利号 CN 109661071 B, 授权公告日 2016-03-12.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of <I>N</I>,<I>N</I>-Dimethylindoaniline in Pharmaceutical Formulations". Chromatographia, 2023, 1837, (5), 7596-7611.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>N</I>,<I>N</I>-Dimethylindoaniline as an Impurity". Food Chem., 2012, 2162, 8845-8867.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 2150-58-5 2,5-Cyclohexadien-1-one, 4-(p-dimethylaminophenyl)imino- 2,5-Cyclohexadien-1-one, 4-((4-(dimethylamino)phenyl)imino)- 4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-one Indoaniline, N,N-dimethyl- (8CI) 4-13-00-00127 (Beilstein Handbook Reference) BRN 2109219 4-(p-Dimethylaminophenyl)imino-2,5-cyclohexadiene-1-one N,N-Dimethylindoaniline EINECS 218-434-6 Indoaniline, N,N-dimethyl- NSC 400538 NSC 402443 Phenol Blue Using HRMS and NMR". Phytochemistry, 2015, 398, (5), 8784-8793.
  4. Chen X Y, Liu M, Zhao W Q. "Forced Degradation Studies to Evaluate <I>N</I>,<I>N</I>-Dimethylindoaniline Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2021, 734, (11), 2500-2523.

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