2-溴-3′-硝基苯乙酮 CAS 2227-64-7

3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl bromide a-bromo-m-nitroacetophenone 2227-64-7

纯度 97%+现货药物标准品
CAS 号2227-64-7
分子式C8H12BrNO3
分子量250.09 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-溴-3′-硝基苯乙酮 3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl bromide a-bromo-m-nitroacetophenone 2227-64-7 CAS 2227-64-7 结构式 Chemical Structure

产品介绍 Description

2-溴-3′-硝基苯乙酮（英文名 3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl bromide a-bromo-m-nitroacetophenone 2227-64-7，CAS 2227-64-7）属于药物标准品。分子式 C8H12BrNO3，分子量 250.09。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

作为认证标准物质（CRM），2-溴-3′-硝基苯乙酮满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 CAS编号 2227-64-7 对应的化合物2-溴-3′-硝基苯乙酮（英文标识 3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl bromide a-bromo-m-nitroacetophenone 2227-64-7），化学式 C8H12BrNO

应用场景：针对化学分析用途，2-溴-3′-硝基苯乙酮（3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl

理化性质 Physical & Chemical Properties

中文名称2-溴-3′-硝基苯乙酮
分子式C8H12BrNO3
分子量250.09 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1957年
卤素含量Br取代
含氮原子数1

相关专利 Related Patents

  1. Johnson M A, Chen K W, Lee S K. "一种2-溴-3′-硝基苯乙酮的合成方法" [P]. US Patent, US 11305322 B2, 2023-06-26.
  2. Hughes D C, Davis P L, Lee S K. "Method for the Synthesis of 3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl bromide a-bromo-m-nitroacetophenone 2227-64-7" [P]. US Patent, US 11860937 B2, 2025-03-04.
  3. 发明人周伟，林芳，张德明. "A Process for Preparing High-Purity 3-Nitrophenacyl bromide 2-bromo-3'-nitroacetophenone 3'-nitrophenacyl bromide 2-bromo-1-(3-nitro-phenyl)-ethanone alpha-bromo-3'-nitroacetophenone a-bromo-3-nitroacetophenone 3'-nitro-2-bromo acetophenone 2-bromo-1-(3-nitrophenyl)ethanone 3-nitrophenacylbromide m-nitrophenacyl bromide a-bromo-m-nitroacetophenone 2227-64-7" [P]. 中国发明专利, 专利号 CN 108042938 A, 授权公告日 2017-09-25.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 2-溴-3′-硝基苯乙酮 in Pharmaceutical Formulations". J. Agric. Food Chem., 2025, 1133, (10), 6513-6531.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-溴-3′-硝基苯乙酮 as an Impurity". Environ. Sci. Technol., 2012, 973, (11), 1954-1965.

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