4-三甲基苯胺 CAS 22948-06-7
22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Triphenylmethyl)benzenamine p-Tritylaniline 4-(Trityl)aniline
| CAS 号 | 22948-06-7 |
| 分子式 | C25H45N |
| 分子量 | 359.63 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的4-三甲基苯胺（22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Triphenylmethyl)benzenamine p-Tritylaniline 4-(Trityl)aniline）为药物标准品，CAS 登记号 22948-06-7，分子式 C25H45N，分子量 359.63。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
依据分子式为 C25H45N 的4-三甲基苯胺结构特征，其分子内含含氮杂环结构，含氰基，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 359.63 g/mol 这一参数对质谱检测中的分子离子峰识别具有直接参考价值。由于碳链较长，脂溶性良好，该化合物在Octanol-Water分配系数测试中倾向于有机相。 化学式为 C25H45N 的4-三甲基苯胺（22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Triphenylmethyl)benzenamine p-Trit
应用场景：4-三甲基苯胺（22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Tripheny
理化性质 Physical & Chemical Properties
| 中文名称 | 4-三甲基苯胺 |
| 分子式 | C25H45N |
| 分子量 | 359.63 g/mol |
| 外观形态 | 类白色至淡黄色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯 |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 4.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1963年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人罗永刚，钱学锋，陈志强. "一种4-三甲基苯胺的合成方法" [P]. 中国发明专利, 专利号 CN 113825170 B, 授权公告日 2017-02-21.
- 发明人刘建华，孙丽萍，罗永刚. "Method for the Synthesis of 22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Triphenylmethyl)benzenamine p-Tritylaniline 4-(Trityl)aniline" [P]. 中国发明专利, 专利号 CN 113765372 A, 授权公告日 2019-08-26.
- 发明人周伟，唐晓军，郑宇鹏. "A Process for Preparing High-Purity 22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Triphenylmethyl)benzenamine p-Tritylaniline 4-(Trityl)aniline" [P]. 中国发明专利, 专利号 CN 115862103 A, 授权公告日 2021-02-08.
参考文献 Literature
- Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of 4-三甲基苯胺 in Pharmaceutical Formulations". Anal. Methods, 2019, 559, (1), 3098-3110.
- Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-三甲基苯胺 as an Impurity". Molecules, 2025, 1991, 4349-4367.
- Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 22948-06-7 Benzenamine, 4-(triphenylmethyl)- 4-(Triphenylmethyl)aniline 4-12-00-03511 (Beilstein Handbook Reference) p-Aminotetraphenylmethane 4-Aminotetraphenylmethane BRN 2750328 EINECS 245-346-5 NSC 2085 p-Toluidine, alpha,alpha,alpha-triphenyl- Triphenyl(p-aminophenyl)methane 4-(Triphenylmethyl)benzenamine p-Tritylaniline 4-(Trityl)aniline Using HRMS and NMR". J. Agric. Food Chem., 2025, 2087, (1), 6803-6824.
- Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate 4-三甲基苯胺 Profile in Drug Substances According to ICH Guidelines". J. Sep. Sci., 2024, 1141, 1426-1456.
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