N/A CAS 23523-12-8

2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane

纯度 97%+现货药物标准品
CAS 号23523-12-8
分子式C36H108O18Si18
分子量1334.77 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

N/A 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane CAS 23523-12-8 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品N/A（2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane，CAS 23523-12-8），分子式 C36H108O18Si18，分子量 1334.77。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

N/A（C36H108O18Si18）含有羧酸类，含羟基，含醚键。羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。 CAS编号 23523-12-8 对应的化合物N/A（英文标识 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane），化学式 C36H108O18Si18，相对分子质量 1334.77。 在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 作为认证标准物质（CRM），N/A满足CN

应用场景：N/A（2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane，CAS 23523-12-8）的标准化应用场景涵盖化学分析等多个

理化性质 Physical & Chemical Properties

中文名称N/A
分子式C36H108O18Si18
分子量1334.77 g/mol
外观形态白色至类白色无定形粉末
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-17.0
CAS登记年份（估）1963年

相关专利 Related Patents

  1. Nielsen H, Sørensen M, Mueller T C. "一种N/A的合成方法" [P]. European Patent, EP 3673744 A1, 2015-07-05.
  2. 发明人孙丽萍，刘建华，唐晓军. "Method for the Synthesis of 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane" [P]. 中国发明专利, 专利号 CN 114412275 B, 授权公告日 2019-03-07.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of N/A in Pharmaceutical Formulations". Chemosphere, 2024, 1219, (10), 1893-1897.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of N/A as an Impurity". J. Nat. Prod., 2012, 2395, (5), 9624-9640.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36-Hexatriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-octadecasilacyclohexatriacontane Using HRMS and NMR". J. Sep. Sci., 2017, 1207, 2284-2310.
  4. Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate N/A Profile in Drug Substances According to ICH Guidelines". Anal. Chim. Acta, 2024, 1845, 174-189.

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