聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液 CAS 25087-06-3

25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyvinyl-methyl-ether/maleic-acid ethyl ester copolymer Maleic acid monoethyl ester-vinyl methyl ether copolymer, minimum average molecular weight (in amu), 46,000

纯度 97%+现货药物标准品
CAS 号25087-06-3
分子式C6H8O4 C3H6O
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液 25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyvinyl-methyl-ether/maleic-acid ethyl ester copolymer Maleic acid monoethyl ester-vinyl methyl ether copolymer, minimum average molecular weight (in amu), 46,000 CAS 25087-06-3 结构式 Chemical Structure

产品介绍 Description

聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液（英文名 25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyvinyl-methyl-ether/maleic-acid ethyl ester copolymer Maleic acid monoethyl ester-vinyl methyl ether copolymer, minimum average molecular weight (in amu), 46,000，CAS 25087-06-3）属于药物标准品。分子式 C6H8O4 C3H6O。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C6H8O4 C3H6O 的聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液（25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyviny

应用场景：从实际应用出发，聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液（CAS 25087-06-3）在化学分析中作为关键的基准对照物质。 推荐以聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于阴凉处（≤25°C）保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环

理化性质 Physical & Chemical Properties

中文名称聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液
分子式C6H8O4 C3H6O
分子量202.21 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1964年

相关专利 Related Patents

  1. 发明人徐明华，刘建华，杨光. "一种聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液的合成方法" [P]. 中国发明专利, 专利号 CN 112728888 B, 授权公告日 2016-05-21.
  2. Anderson J P, Mueller T, Stevens L M. "Method for the Synthesis of 25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyvinyl-methyl-ether/maleic-acid ethyl ester copolymer Maleic acid monoethyl ester-vinyl methyl ether copolymer, minimum average molecular weight (in amu), 46,000" [P]. US Patent, US 10064146 B2, 2015-06-11.
  3. 发明人唐晓军，周伟，李文辉. "A Process for Preparing High-Purity 25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyvinyl-methyl-ether/maleic-acid ethyl ester copolymer Maleic acid monoethyl ester-vinyl methyl ether copolymer, minimum average molecular weight (in amu), 46,000" [P]. 中国发明专利, 专利号 CN 112285847 B, 授权公告日 2016-06-14.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液 in Pharmaceutical Formulations". Food Chem., 2021, 1032, (6), 695-720.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液 as an Impurity". J. Sep. Sci., 2010, 2163, 8262-8269.
  3. Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 25087-06-3 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethane 2-Butenedioic acid (Z)-, monoethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, 1-ethyl ester, polymer with methoxyethene 2-Butenedioic acid (2Z)-, monoethyl ester, polymer with methoxyethene Ethyl ester of pvm/MA copolymer Gantrez ES 225 ES 225 Gantrez Polyvinyl-methyl-ether/maleic-acid ethyl ester copolymer Maleic acid monoethyl ester-vinyl methyl ether copolymer, minimum average molecular weight (in amu), 46,000 Using HRMS and NMR". Anal. Chim. Acta, 2023, 496, 3700-3729.
  4. Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate 聚(乙烯基甲醚-<I>alt</I>-马来酸单乙酯) 溶液 溶液 Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2019, 841, (4), 885-904.

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