聚维酮碘 CAS 25655-41-8
85H0HZU99M 25655-41-8 E-Z Scrub UNII-85H0HZU99M Betadin Povidone-iodine Iodopoly(vinyl pyrrolidinone) Polyvinylpyrrolidone-iodine complex Iodinated poly(vinylpyrrolidone) Iodine-poly(vinylpyrrolidinone) Iodine-polyvinylpyrrolidone complex 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex Poly(vinylpyrrolidinone) iodide Poly(vinylpyrrolidinone)-iodine complex Poly(vinylpyrrolidone) - iodine complex Polyvinylpyrrolidone compound with iodine Poly(vinylpyrrolidone)-iodine adduct Povadyne Isobetadyne Isodine NSC 26245 1-Vinyl-2-pyrrolidinone polymer, compound with iodine Povidone iodine Povidone-lodine Proviodine PVP-I Pvp-1 PVP iodine PVP-Iodine PVP-Iodine, 30-06 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine Traumasept Ultradine Videne 1-Vinyl-2-pyrrolidinone polymers, iodine complex 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with iodine (8CI) Argentyne Betadine Betadine (VAN) Betaisodona Braunol Braunosan H Bridine Disadine D.P. Disphex Efo-dine 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine HSDB 6831 Inadine 1-Vinyl-2-pyrrolidinone polymer W/iodine Polyvinylpyrrolidone - iodine complex Povidone-iodine [USP:BAN:JAN] CCRIS 9290 E-Z Prep E-Z Prep 220 E-Z Scrub 201 E-Z Scrub 241
| CAS 号 | 25655-41-8 |
| 分子式 | I2 C6H9NO |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
聚维酮碘（85H0HZU99M 25655-41-8 E-Z Scrub UNII-85H0HZU99M Betadin Povidone-iodine Iodopoly(vinyl pyrrolidinone) Polyvinylpyrrolidone-iodine complex Iodinated poly(vinylpyrrolidone) Iodine-poly(vinylpyrrolidinone) Iodine-polyvinylpyrrolidone complex 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex Poly(vinylpyrrolidinone) iodide Poly(vinylpyrrolidinone)-iodine complex Poly(vinylpyrrolidone) - iodine complex Polyvinylpyrrolidone compound with iodine Poly(vinylpyrrolidone)-iodine adduct Povadyne Isobetadyne Isodine NSC 26245 1-Vinyl-2-pyrrolidinone polymer, compound with iodine Povidone iodine Povidone-lodine Proviodine PVP-I Pvp-1 PVP iodine PVP-Iodine PVP-Iodine, 30-06 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine Traumasept Ultradine Videne 1-Vinyl-2-pyrrolidinone polymers, iodine complex 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with iodine (8CI) Argentyne Betadine Betadine (VAN) Betaisodona Braunol Braunosan H Bridine Disadine D.P. Disphex Efo-dine 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine HSDB 6831 Inadine 1-Vinyl-2-pyrrolidinone polymer W/iodine Polyvinylpyrrolidone - iodine complex Povidone-iodine [USP:BAN:JAN] CCRIS 9290 E-Z Prep E-Z Prep 220 E-Z Scrub 201 E-Z Scrub 241，CAS 号 25655-41-8）是 CATO 佳途自主生产的药物标准品，分子式 I2 C6H9NO。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
从化学结构特征来看，聚维酮碘的分子骨架中包含酰胺类，含羟基，含醚键，含碘取代。该化合物的不饱和度为2.0，表明结构中存在约2个环或双键等价单元。分子量为364.94 g/mol，属于较高分子量化合物。卤素原子的引入增加了化合物的电负性，在ECD（电子捕获检测器）中具有优良的响应灵敏度。 化学式为 I2 C6H9NO 的聚维酮碘（85H0HZU99M 25655-41-8 E-Z Scrub UNII-85H0HZU99M Betadin Povidone-iodine Iodopoly(vinyl pyrrolidinone) Polyvinylpyrrolidone-iodine complex Iodinated poly(vinylpyrrolidone) Iodine-poly(vinylpyrrolidinone) Iodine-polyvinylpyrrolidone complex 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodin
应用场景：聚维酮碘（85H0HZU99M 25655-41-8 E-Z Scrub UNII-85H0HZU99M Betadin Povidone-iodine Iodopoly(vinyl pyrrolidinone) Polyvinylpyrrolidone-iodine complex Iodinated poly(vinylpyrrolidone) Iodine-poly(vinylpyrrolidinone) Iodine-polyvinylpyrrolidone complex 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine Poly
理化性质 Physical & Chemical Properties
| 中文名称 | 聚维酮碘 |
| 分子式 | I2 C6H9NO |
| 分子量 | 364.94 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.0 |
| CAS登记年份（估） | 1964年 |
| 卤素含量 | I取代 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人何建平，郑宇鹏，李文辉. "一种聚维酮碘的合成方法" [P]. 中国发明专利, 专利号 CN 110314624 A, 授权公告日 2022-04-19.
- Schröder R, Sørensen M, Jørgensen K. "Method for the Synthesis of 85H0HZU99M 25655-41-8 E-Z Scrub UNII-85H0HZU99M Betadin Povidone-iodine Iodopoly(vinyl pyrrolidinone) Polyvinylpyrrolidone-iodine complex Iodinated poly(vinylpyrrolidone) Iodine-poly(vinylpyrrolidinone) Iodine-polyvinylpyrrolidone complex 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex Poly(vinylpyrrolidinone) iodide Poly(vinylpyrrolidinone)-iodine complex Poly(vinylpyrrolidone) - iodine complex Polyvinylpyrrolidone compound with iodine Poly(vinylpyrrolidone)-iodine adduct Povadyne Isobetadyne Isodine NSC 26245 1-Vinyl-2-pyrrolidinone polymer, compound with iodine Povidone iodine Povidone-lodine Proviodine PVP-I Pvp-1 PVP iodine PVP-Iodine PVP-Iodine, 30-06 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine Traumasept Ultradine Videne 1-Vinyl-2-pyrrolidinone polymers, iodine complex 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with iodine (8CI) Argentyne Betadine Betadine (VAN) Betaisodona Braunol Braunosan H Bridine Disadine D.P. Disphex Efo-dine 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine HSDB 6831 Inadine 1-Vinyl-2-pyrrolidinone polymer W/iodine Polyvinylpyrrolidone - iodine complex Povidone-iodine [USP:BAN:JAN] CCRIS 9290 E-Z Prep E-Z Prep 220 E-Z Scrub 201 E-Z Scrub 241" [P]. European Patent, EP 3547681 A1, 2017-04-21.
参考文献 Literature
- Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 聚维酮碘 in Pharmaceutical Formulations". Molecules, 2011, 2234, (9), 7742-7765.
- O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚维酮碘 as an Impurity". Anal. Chim. Acta, 2016, 1350, (3), 8172-8176.
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