<I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺 CAS 26227-73-6
26227-73-6 O69C41149Y N-(4-Methoxybenzylidene)-4-butylaniline Aniline, p-butyl-N-(p-methoxybenzylidene)- Benzenamine, 4-butyl-N-((4-methoxyphenyl)methylene)- Benzeneamine, 4-butyl-N-((4-methoxyphenyl)methylene)- (9CI) 4-Butyl-N-((4-methoxyphenyl)methylene)benzenamine 4-Methoxybenzilidine-4'-N-butylaniline N-(4'-Methoxybenzylidene)-4-butylaniline DL 1047 N BRN 0790714 CCRIS 4668 EINECS 247-527-4 MBBA N-(p-Methoxybenzylidene)-p-butylaniline 4-Methoxybenzylidene-4'-n-butylaniline N-(4-Methoxybenzylidine)-4'-butylaniline UNII-O69C41149Y
| CAS 号 | 26227-73-6 |
| 分子式 | C18H33NO |
| 分子量 | 279.46 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
<I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺（26227-73-6 O69C41149Y N-(4-Methoxybenzylidene)-4-butylaniline Aniline, p-butyl-N-(p-methoxybenzylidene)- Benzenamine, 4-butyl-N-((4-methoxyphenyl)methylene)- Benzeneamine, 4-butyl-N-((4-methoxyphenyl)methylene)- (9CI) 4-Butyl-N-((4-methoxyphenyl)methylene)benzenamine 4-Methoxybenzilidine-4'-N-butylaniline N-(4'-Methoxybenzylidene)-4-butylaniline DL 1047 N BRN 0790714 CCRIS 4668 EINECS 247-527-4 MBBA N-(p-Methoxybenzylidene)-p-butylaniline 4-Methoxybenzylidene-4'-n-butylaniline N-(4-Methoxybenzylidine)-4'-butylaniline UNII-O69C41149Y，CAS 号 26227-73-6）是 CATO 佳途自主生产的药物标准品，分子式 C18H33NO，分子量 279.46。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 CAS编号 26227-73-6 对应的化合物<I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺（英文标识 26227-73-6 O69C41149Y N-(4-Methoxybenzylidene)-4-butylaniline Aniline, p-butyl-N-(p-methoxybenzylidene)- Benzenamine, 4-butyl-N-((4-methoxyphenyl)methylene)- Benzeneamine, 4-butyl-N-((4-methoxyphenyl)methylene)- (9CI) 4-Butyl-N-((4-methoxyphenyl)methylene)benzenamine 4-Methoxybenzilidine-4'-N-butylaniline N-(4'-Methoxybenzylidene)-4-butylaniline DL 1047 N BRN 07
应用场景：针对化学分析用途，<I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺（26227-73-6 O69C41149Y N-(4-Methoxybenzylidene)-4-butylaniline Aniline, p-butyl-N-(p-methoxybenzylidene)- Benzenamine, 4-butyl-N-((4-methoxyphenyl)methylene)- Benzeneamine, 4-butyl-N-((4-methoxyphenyl)methylene)- (9CI) 4-Butyl-N-((4-methoxyphenyl)methylene)benzena
理化性质 Physical & Chemical Properties
| 中文名称 | <I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺 |
| 分子式 | C18H33NO |
| 分子量 | 279.46 g/mol |
| 外观形态 | 白色至淡黄色低熔点固体 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 3.0 |
| UV特征 | 有紫外吸收 |
| CAS登记年份（估） | 1964年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人钱学锋，林芳，李文辉. "一种<I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺的合成方法" [P]. 中国发明专利, 专利号 CN 109689349 B, 授权公告日 2021-04-25.
- Schröder R, Nowak P, Nielsen H. "Method for the Synthesis of 26227-73-6 O69C41149Y N-(4-Methoxybenzylidene)-4-butylaniline Aniline, p-butyl-N-(p-methoxybenzylidene)- Benzenamine, 4-butyl-N-((4-methoxyphenyl)methylene)- Benzeneamine, 4-butyl-N-((4-methoxyphenyl)methylene)- (9CI) 4-Butyl-N-((4-methoxyphenyl)methylene)benzenamine 4-Methoxybenzilidine-4'-N-butylaniline N-(4'-Methoxybenzylidene)-4-butylaniline DL 1047 N BRN 0790714 CCRIS 4668 EINECS 247-527-4 MBBA N-(p-Methoxybenzylidene)-p-butylaniline 4-Methoxybenzylidene-4'-n-butylaniline N-(4-Methoxybenzylidine)-4'-butylaniline UNII-O69C41149Y" [P]. European Patent, EP 3474660 A1, 2016-11-03.
参考文献 Literature
- Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of <I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺 in Pharmaceutical Formulations". Anal. Chim. Acta, 2015, 326, (9), 5253-5264.
- Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺 as an Impurity". Anal. Chem., 2010, 1348, (9), 9480-9505.
- Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 26227-73-6 O69C41149Y N-(4-Methoxybenzylidene)-4-butylaniline Aniline, p-butyl-N-(p-methoxybenzylidene)- Benzenamine, 4-butyl-N-((4-methoxyphenyl)methylene)- Benzeneamine, 4-butyl-N-((4-methoxyphenyl)methylene)- (9CI) 4-Butyl-N-((4-methoxyphenyl)methylene)benzenamine 4-Methoxybenzilidine-4'-N-butylaniline N-(4'-Methoxybenzylidene)-4-butylaniline DL 1047 N BRN 0790714 CCRIS 4668 EINECS 247-527-4 MBBA N-(p-Methoxybenzylidene)-p-butylaniline 4-Methoxybenzylidene-4'-n-butylaniline N-(4-Methoxybenzylidine)-4'-butylaniline UNII-O69C41149Y Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2016, 360, 1888-1895.
- Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate <I>N</I>-(4-甲氧基苯亚甲基）-4-丁基苯胺 Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2022, 2293, (3), 2855-2879.
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