甲基环戊二烯二聚体 CAS 26472-00-4

26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247-724-5

纯度 97%+现货药物标准品
CAS 号26472-00-4
分子式C12H16
分子量160.26 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

甲基环戊二烯二聚体 26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247-724-5 CAS 26472-00-4 结构式 Chemical Structure

产品介绍 Description

甲基环戊二烯二聚体（26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247-724-5，CAS 号 26472-00-4）是 CATO 佳途自主生产的药物标准品，分子式 C12H16，分子量 160.26。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在质量保证方面，甲基环戊二烯二聚体的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 甲基环戊二烯二聚体（26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247

应用场景：甲基环戊二烯二聚体（26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-

理化性质 Physical & Chemical Properties

中文名称甲基环戊二烯二聚体
分子式C12H16
分子量160.26 g/mol
外观形态类白色至淡黄色低熔点固体
纯度97%+
储存条件2-8°C冷藏保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1964年

相关专利 Related Patents

  1. 发明人张德明，孙丽萍，郭海燕. "一种甲基环戊二烯二聚体的合成方法" [P]. 中国发明专利, 专利号 CN 112042465 B, 授权公告日 2022-03-04.
  2. 发明人马晓峰，张德明，李文辉. "Method for the Synthesis of 26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247-724-5" [P]. 中国发明专利, 专利号 CN 112981888 B, 授权公告日 2017-06-12.
  3. 发明人沈红梅，陈志强，徐明华. "A Process for Preparing High-Purity 26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247-724-5" [P]. 中国发明专利, 专利号 CN 114095954 A, 授权公告日 2023-09-17.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 甲基环戊二烯二聚体 in Pharmaceutical Formulations". J. Chromatogr. A, 2024, 1028, (3), 5910-5929.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 甲基环戊二烯二聚体 as an Impurity". Chemosphere, 2012, 2334, (3), 1619-1627.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 26472-00-4 Methylcyclopentadiene dimer 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydrodimethyl- 4,7-Methanoindene, 3a,4,7,7a-tetrahydrodimethyl- Methylcyclopentadiene Bis(methylcyclopentadiene) Dimethyldicyclopentadiene EINECS 247-724-5 3a,4,7,7a-Tetrahydrodimethyl-4,7-methanoindene 3a,4,7,7a-Tetrahydrodimethyl-4,7-methano-1H-indene EC 247-724-5 Using HRMS and NMR". Biomed. Chromatogr., 2020, 665, 9464-9480.
  4. Yang F, Sun W, Liu J. "Forced Degradation Studies to Evaluate 甲基环戊二烯二聚体 Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2012, 1528, (1), 3897-3910.

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