2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt CAS 267228-70-6
(9Z)-9-Octadecenoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester monoammonium salt 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1 inverted exclamation marka-rac-glycerol) ammonium salt 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ammonium salt 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt 267228-70-6 L-|A-Phosphatidyl-DL-glycerol, |A-oleoyl-|A-palmitoyl ammonium salt PG(16:0/18:1(9Z)) POPG-NH4
| CAS 号 | 267228-70-6 |
| 分子式 | C40H77O10P H3N |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt（(9Z)-9-Octadecenoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester monoammonium salt 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1 inverted exclamation marka-rac-glycerol) ammonium salt 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ammonium salt 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt 267228-70-6 L-|A-Phosphatidyl-DL-glycerol, |A-oleoyl-|A-palmitoyl ammonium salt PG(16:0/18:1(9Z)) POPG-NH4）是药物分析与质量控制领域常用的药物标准品，CAS 号 267228-70-6。分子式 C40H77O10P H3N。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。
推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt（(9Z)-9-Octadecenoic acid (1R)-1-(2,3-dihydroxypropoxy)hydroxyphosphinyloxymethyl-2-(1-oxohexadecyl)oxyethyl ester monoammonium salt 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1 inverted exclamation marka-rac-glycerol) ammonium salt 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ammonium salt 2-Oleoyl-1-palmitoyl-sn-glycero-3-pho
应用场景：从实际应用出发，2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt（CAS 267228-70-6）在化学分析中作为关键的基准对照物质。 推荐以2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储
理化性质 Physical & Chemical Properties
| 中文名称 | 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt |
| 分子式 | C40H77O10P H3N |
| 分子量 | 766.05 g/mol |
| 外观形态 | 白色至类白色无定形粉末 |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.5 |
| CAS登记年份（估） | 2025年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人马晓峰，何建平，郑宇鹏. "一种2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt的合成方法" [P]. 中国发明专利, 专利号 CN 115944324 B, 授权公告日 2020-06-26.
- 发明人沈红梅，张德明，钱学锋. "Method for the Synthesis of (9Z)-9-Octadecenoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester monoammonium salt 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1 inverted exclamation marka-rac-glycerol) ammonium salt 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ammonium salt 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt 267228-70-6 L-|A-Phosphatidyl-DL-glycerol, |A-oleoyl-|A-palmitoyl ammonium salt PG(16:0/18:1(9Z)) POPG-NH4" [P]. 中国发明专利, 专利号 CN 117967035 A, 授权公告日 2018-12-10.
参考文献 Literature
- Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2024, 2229, (8), 3052-3074.
- Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt as an Impurity". Biomed. Chromatogr., 2011, 1822, 1816-1832.
- Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of (9Z)-9-Octadecenoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester monoammonium salt 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1 inverted exclamation marka-rac-glycerol) ammonium salt 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ammonium salt 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt 267228-70-6 L-|A-Phosphatidyl-DL-glycerol, |A-oleoyl-|A-palmitoyl ammonium salt PG(16:0/18:1(9Z)) POPG-NH4 Using HRMS and NMR". Sci. Total Environ., 2017, 1778, 404-429.
- Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2019, 157, 8121-8144.
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