CAS 269398-81-4

(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid

纯度 97%+现货药物标准品
CAS 号269398-81-4
分子式C26H25NO4
分子量415.48 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid CAS 269398-81-4 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品（(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid，CAS 269398-81-4），分子式 C26H25NO4，分子量 415.48。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

与同类药物标准品相比，的分子量为415.48 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 （(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-9H-fluoren-9-ylmethoxy(oxo)methylamino-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid），CAS注册编号 269398-81-4，化学分子式为 C26H25NO4，分子量 415.48 g/mol。 受分子结构中甾体骨架，酰胺类，含羟基，含醚键的影

应用场景：针对化学分析用途，（(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3- 9H-fluoren-9-ylmethoxy(oxo)methyl amino -4-(2-methylphenyl)butano

理化性质 Physical & Chemical Properties

中文名称
分子式C26H25NO4
分子量415.48 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）15.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
含氮原子数1

相关专利 Related Patents

  1. 发明人朱建伟，林芳，罗永刚. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 113715233 A, 授权公告日 2016-11-19.
  2. Patel M V, Thompson G K, Williams B T. "Method for the Synthesis of (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid" [P]. US Patent, US 11959572 B2, 2021-06-15.
  3. 发明人冯建国，周伟，朱建伟. "A Process for Preparing High-Purity (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid" [P]. 中国发明专利, 专利号 CN 109181750 B, 授权公告日 2025-03-02.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Sci. Total Environ., 2011, 992, 8422-8427.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Chem., 2015, 164, (1), 6540-6554.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylphenyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(o-tolyl)butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(2-methylphenyl)butanoic acid 269398-81-4 Fmoc-(R)-3-Amino-4-(2-methylphenyl)-butyric acid Using HRMS and NMR". Biomed. Chromatogr., 2023, 2224, 4954-4963.

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